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  • ThesisItemOpen Access
    ULTRASTRUCTURAL STUDIES OF EPITHELIUM OF LOWER RESPIRATORY TRACT IN ADULT NON-DESCRIPT INDIAN GOAT (Capra hircus)
    (SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2006-12) RANJITH KUMAR, S; Nagamalleswari, Y(MAJOR); Pramod Kumar, D; Girish Kumar, V
    ABSTRACT: The lower respiratory tract, defined anatomically as the region of respiratory system including trachea, bronchi, bronchioles and alveoli, were studied in Indian goat by means of both scanning and transmission electron microscopy. The epithelium of trachea was comprised of ciliated, non-ciliated, brush and basal cells. Ciliated cells were columnar and contained numerous cilia, round and elongated mitochondria and many vacuoles. Non-ciliated cells or mucous cells were columnar with basal nucleus, irregular sized mitochondria, and mucous granules of varying density. Brush cells were columnar with short microvilli, mucous granules, mitochondria, golgi complex, granular endoplasmic reticulum (GER) and smooth endoplasmic reticulum (SER). Basal cells were arranged in two rows with few mitochondria, secretory vesicles and endoplasmic reticulum. Bronchial epithelium was lined with ciliated cells, mucous cells and basal cells. Characteristics of these cells were similar to trachea. But ciliation was less when compared to trachea. Epithelium of terminal bronchiole consists of two cell types. Ciliated cells were cuboidal contained short cilia, round mitochondria and many vacuoles. Non-ciliated cells or clara cells were protruded into lumen. Numerous large mitochondria and membrane bound inclusions were notable in non-ciliated cells or clara cells. Respiratory bronchioles were characterized by low cuboidal epithelium. The cells in this region contained large mitochondria, well developed golgi apparatus and unusual tubular structures. The epithelium of alveolar duct and alveoli was composed of type I and type II pneumocytes. Classical type I pneumocyte was squamous and had scanty cytoplasm which showed absence of cellular organelles. Type II pneumocytes were characterized by the presence of lamellar bodies and numerous mitochondria.