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ThesisItem Open Access STUDIES ON THE EFFECTS OF SUPPLEMENTATION OF CERTAIN PROBIOTICS AND ENZYMES ON THE PERFORMANCE OF BROILERS(SRI VENKATESWARA VETERINARY UNIVERSITY TIRUPATI - 517 502. (A.P.) INDIA, 2005-09) BALACHANDAR, J; SUDHAKARA REDDY, P(MAJOR); SATYANARAYNA REDDY, P.V.V; PARTHASARATHY, MABSTRACT : An experiment was conducted with three types of commercial probiotics and an enzyme mixture either alone or in combination in eight dietary treatments to study the performance of broilers. The body weight gain was significantly (P < 0.01) affected in broiler during starter, finisher and overall periods. However, the best weight gain was noticed in probiotic combined with enzymes (T8) group compared to control (T1) group throughout the experimental period. The feed intake was not significantly affected in broilers during starter period but, it was affected significantly (P < 0.01) among different groups during finisher and entire period. It was observed that higher weight gain groups had roportionately more feed intake especially during finisher and entire periods. The feed efficiency was significantly different (P < 0.01 & P < 0.05) among treatment groups during all the growth phases. Furthermore, the broilers fed probiotic combined with enzymes group (T8) exerted the best feed efficiency compared to control group (T1). Eventhough the feed cost / kg live weight gain was significantly (P < 0.01) different among treatment groups, the feed cost / kg live weight gain was the lowest in T8 group compared to other groups. The probiotics or enzymes alone and their combination at recommended levels in broiler diets did not influence the carcass traits, haemoglobin and serum protein levels. The immune response (HI titre) to ND vaccination did not differ significantly, but it was above protective levels in broilers irrespective of different dietary treatments. It is inferred that probiotics and enzymes either alone or in combination at recommended levels in broiler diets can be supplemented safely without affecting the performance of broilers.