Browsing by Author "Kulkarni, Harish"
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ArticleItem Open Access Analgesic and adjunct actions of nalbuphine hydrochloride in xylazine or xylazine and acepromazine premedicated horses(2015-10) Kulkarni, Harish; Justin William, B; George, Ravi Sundar , et al.; TANUVASThe study was conducted in eighteen clinical cases of horses for diagnostic and surgical procedures requiring general anaesthesia were randomly divided into three groups, group I, group II and group III, each consisting of six cases. All the horses were premedicated with glycopyrrolate at the dose rate of 0.02 mg/kg body weight, intravenously. Horses in Group I and Group II were administered xylazine hydrochloride at the dose rate of 1.10 mg/kg body weight intravenously, whereas in Group III at the dose rate of 0.50 mg/kg body weight intravenously. In Group III, acepromazine was injected after xylazine administration, at the dose rate of 0.02mg/kg body weight, intravenously. Before induction of anaesthesia, nalbuphine hydrochloride was administered for Group II and Group III at the dose rate of 0.75 mg/kg body weight intravenously. Ketamine hydrochloride was administered intravenously to induce anaesthesia at the dose rate of 2.20 mg/kg body weight and maintained with 0.50 mg/kg body weight in required cases to maintain for duration of 15 ± 1.04 minutes. The mean time for induction in group I, group II and group III were 1.78 ± 0.27, 1.73 ± 0.10 and 1.85 ± 0.28 minutes respectively. The mean total number of additional doses of ketamine for standard duration of 15 ± 1.04 minutes surgery required in group I, group II and group III were 5.00 ± 0.36, 1.66 ± 0.33 and 2.00 ± 0.36 respectively. The quality of induction was 100 per cent smooth in group III, 83.33 per cent smooth and 16.67 per cent rough in group II and 66.66 per cent smooth and 33.34 per cent rough in group I. The quality of analgesia in group I, group II and group III were 2.83 ± 0.47, 1.83 ± 0.30 and 1.33 ± 0.21 respectively. The quality of muscle relaxation in group I, group II and group III were 3.16 ± 0.30, 1.50 ± 0.22 and 1.33 ± 0.21 respectively. The mean time for recovery in group I, group II and group III were 23.00 ± 1.52, 33.00 ± 0.93 and 41.98 ± 1.32 minutes respectively. The mean number of attempts for unassisted standing in group I, group II and group III were 6.66 ± 0.71, 5.00 ± 0.57 and 5.00 ± 0.36 respectively. The quality of recovery was 83.33 per cent smooth and 16.67 per cent rough in group III, 66.66 per cent smooth and 33.34 per cent rough in group II and 50.00 per cent smooth and 50.00 per cent rough in group I. None of the animals in any groups showed any intra and post operative complication.ArticleItem Open Access Evisceration of Tongue in a Giriraja Cock (Gallus domesticus)(Indian Journal of Veterinary Surgery, 2014-12) George, Ravi Sundar; Kulkarni, Harish; William, B. Justin; TANUVASCock fighting is a folk sport in rural areas and now-a-days it has become more popular in urban cities too. Traumatic injuries to cock during the fight may be fatal if it involves severing of major blood vessels of visceral organs. However, non-fatal injuries may traumatise the eyes, skin, beak and other body parts and may lead to evisceration of organs. This paper reports a case of eviscerated tongue in a fowl and its surgical management.ArticleItem Open Access Haemato-biochemical changes during nalbuphine xylazineacepromazine- ketamine anaesthesia in horses(Indian Society for Veterinary Surgery, 2015-12) Kulkarni, Harish; William, Justin; George, Ravi Sundar; Kannan, TA; TANUVASThe objective of the study was to evaluate cardiopulmonary and haematobiochemical changes and stress response associated with administration of nalbuphine HCl during ketamine anaesthesia in horses premedicated with xylazine or xylazine-acepromazine. Eighteen clinical cases of horses brought for diagnostic and surgical procedures requiring general anaesthesia were randomly divided into three groups, I, II and III, each consisting of six animals. All the horses were premedicated with glycopyrrolate 0.02 mg/kg b.wt, i.v. Horses in group I and group II were administered xylazine HCl 1.10 mg/kg b.wt, i.v. In group III, 0.50 mg/kg b.wt xylazine HCl was administered i.v., followed by acepromazine 0.02 mg/kg b.wt, i.v. Before induction of anaesthesia, nalbuphine HCl was administered in group II and group III animals @ 0.75 mg/kg b.wt, i.v. Ketamine HCl was administered i.v. to induce anaesthesia @ 2.20 mg/kg b.wt and maintained with 0.50 mg/ kg b.wt in required cases for duration of 15±1.04 min. The heart rate increased during intraoperative period reached baseline value 6 hr after surgery. The respiratory rate and mean saturated partial pressure of oxygen decreased significantly during intraoperative period. Haemoglobin, PCV, TEC and TLC decreased significantly; the neutrophil and monocyte counts increased and the lymphocyte count decreased significantly during intraoperative and postoperative period in all the groups. The blood glucose, creatinine, plasma cortisol and plasma catalase activity significantly increased during intraoperative period and postoperative period. The total protein values significantly decreased during the intraoperative period in all the groups. To conclude, administration of nalbuphine HCl did not produce any marked changes in cardiopulmonary, haematobiochemical parameters and produced less stress response.ArticleItem Open Access Management of Open Dislocated Metacarpo-Phalangeal Joint in a Calf Using External Skeletal Fixator(Indian Journal of Veterinary Surgery, 2014-06) George, Ravi Sundar; Prasad, A. Arun; Kulkarni, Harish; Ganesh, R.; William, B. Justin; TANUVASThe present case describes the successful use of external skeletal fixator (ESF) to achieve open wound healing and arthrodesis of joint in a calf to salvage the limb following open dislocation of fetlock.ThesisItem Open Access NALBUPHINE HYDROCHLORIDE AS AN ADJUNCT AND ANALGESIC TO KETAMINE ANAESTHESIA IN XYLAZINE OR XYLAZINE AND ACEPROMAZINE PREMEDICATED HORSES(TANUVAS, Chennai, 2013) Kulkarni, Harish; William, B. Justin; George, Ravi Sundar; Kannan, T.A.; TANUVASPain is very intense and debilitating in the horse than any other farm animals and may be primarily responsible for decreased performance, high morbidity and mortality. The use of a good analgesic agent in horses during intra and post-operative surgical procedures will inevitably be of a greater contribution in the field of equine anaesthesia and analgesia.ArticleItem Open Access Surgical Correction of Urethral Prolapse in a Pug(Indian Journal of Veterinary Surgery, 2013-12) Shafiuzama, Mohamed; Kulkarni, Harish; Rajalingam, A.; William, B. Justin; TANUVASAn eight-month-old male pug, weighing 6 kg was presented with a history of protrusion of reddish mass from the tip of penis for the past three days. Clinical examination of the penis revealed urethral prolapse (Fig. 1). The physical and haematobiochemical parameters were within the normal range. Initially the condition was treated by applying icepacks over the prolapsed mass, along with systemic antibiotic and steroids therapy. Elizabethan collar was advised to prevent self licking and trauma to the prolapsed mass. Since there was no improvement in the condition with above treatment, surgical resection of the prolapsed mass was undertaken.ArticleItem Open Access Surgical Management of Perineal Hypospadia in a Dog(Intas Polivet, 2016-01) Krishanan, Gokul; Nagarajan, L.; Kulkarni, Harish; TANUVASA three year old, crossbred intact dog was presented with history of urinary incontinence for past 3 days. On physical examination, external urethral orifice was opening at the ventral surface of the penis rather than the tip of glans with bifid scrotum, hence the case was diagnosed as hypospadias. The cause of the hypospadias is not known, it is presumed that the affected foetus may secret inadequate quantities of testosterone or that there may be inadequate conversion of testosterone to dihydrotestosterone in the target tissues of the urogenital sinus and external genitalia. In the present case, prepupial sheath was incomplete hence reconstructive surgery of the penile prepupial sheath was performed to cover the exposed dry penis and animal recovered uneventfully.