Browsing by Author "Dar, Shahid Hussain"
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ArticleItem Open Access Carpal valgus with elbow sub-luxation secondary to trauma and its surgical treatment in a Labrador dog(2021-12) Dar, Shahid Hussain; Haridos, Pushkin Raj; Ramamurthy, Jayaprakash, et al.,; TANUVASThe alignment deformities of the canine radius are common due to growth disturbances in forelimbs (Fox, 1984). Asymmetric physeal closure of distal radius can result in radial shortening, elbow subluxation and carpal varus or valgus deformities (Balfour et al., 2000). Premature closure of the distal ulnar physis due to trauma is the most common cause of radial growth deformation (O’Brien et al., 1971; Balfour et al., 2000). The present case reports the distal radius asymmetrical premature physeal closure with subluxation of the elbow joint and its surgical management by corrective osteotomy, and fixed with T plate and intramedullary K-wiring of ulna.OtherItem Open Access Comparison of Anaesthetic Effect of Propofol or Etomidate in Butorphanol and Diazepam Premedicated Geriatric Dogs(TANUVAS, Chennai, 2016-12) Dar, Shahid Hussain; Jayaprakash, R.; George, Ravi Sundar; Ganesh, T.N.OtherItem Open Access Corrective Osteotomy of Angular Deformity of the Pelvic Limbs in an African Grey Parrot(TANUVAS, Chennai, 2016-12) Shafiuzama, Mohammad; Dar, Shahid Hussain; Prabha, Neelima Dasari; Kumar, S. Dinesh; Ashok, Chandini G.; George, Ravi SundarThesisItem Open Access Evaluation of Healing Potential of Tissue Engineered Construct in Rabbit Corneal Ulcer Model(SKUAST Kashmir, 2023) Rather, Shakir Ahmad; Dar, Shahid HussainThe present study was aimed to explore the feasibility of development of the natural Acellular Corneal Stromal Disc (ACSD) and its biocompatibility and utility with the bone marrow derived mesenchymal stem cells (BM-MSCs) in repairing induced corneal stromal defect (ulcer) in rabbit model. The study was conducted in two phases viz., A) In vitro development and characterization of ovine sheep decellularized corneal matrix, and evaluation of its biocompatibility with the rabbit cryopreserved BM-MSCs through histopathology, MTT assay and scanning electron microscopy (SEM). B) In vivo evaluation of healing potential of the BM-MSCs seeded ACSD in the rabbit corneal ulcer defect (5 mm diameter) model. The animals (n=48 rabbits) were divided into four (4) groups (n=12 per group). Group I (Control, received no treatment), group II (standard clinical treatment), group III (transplanted with ACSD) and group IV (transplanted with ACSD seeded with cryopreserved allogeneic BM-MSCs). The animals were observed regularly and evaluated at days 14 and 28 using fluorescein dye test, ultrasonography, slit lamp biomicroscopy, histopathology, SEM, and relevant gene (keratocan and ALDH1A1) expression analysis. In vitro study revealed that ACSD were almost completely decellularized and supported the growth and infiltration of BM-MSCs. In vivo experimental corneal ulcer study showed transplantation of ACSD seeded BM-MSCs reduced corneal ulcer size together with improvement in corneal opacity and corneal neovascularization as compared to ACSD (Group III), standard clinical treatment (group II) and control. Ulcer healing evaluated with fluorescein dye test and histopathology revealed better corneal healing in group IV at days 14 and 28 as compared to other three groups. The gene expression revealed that keratocan and ALDH1A1 were highly expressed in group IV as compared to other groups. Corneal ultrasonography showed near normal corneal thickness in groups II and IV at the end of the experimental trial (day 28). In compliance to ultrasonography, SEM also revealed lower cellular infiltration in groups II and IV and regenerated corneal tissue maintained continuity and had least crevices in group IV at the end of study. It is worth mentioning that the complete normalization of corneal ulcer at day 28 was not seen in any group including the group IV. It was concluded that development of sheep corneal tissue engineered construct (ACSD) is a feasible option that supports growth of BM-MSCs. The cell-scaffold assembly potentially heals corneal ulcer although the time required for complete corneal ulcer healing remains to be seen.OtherItem Open Access Mandibular Fracture Management in Dogs - A Review of 15 Cases(TANUVAS, Chennai, 2016-12) Velavan, A.; Kumar, S. Dinesh; Dar, Shahid Hussain; Neelima, Dasari; Jayaprakash, R.; George, Ravi SundarArticleItem Open Access Morphometry of Feline Adipose Tissue Derived Mesenchymal Stem Cells in Culture(Pashupati Foundation India, 2018-12) Nissar, Shazia; Ramesh, Geetha; Kannan, TA; Basha, Sabiha Hayath; Arunmozhi, N; Seerangan, Rangasamy; Dar, Shahid Hussain; TANUVASMorphometric analysis of feline adipose derived mesenchymal stem cells (fAD-MSCs) was done at P1 and P2 (24 and 48 hours) of culture expanded using cover slip culture technique to record the morphometric details. In all the culture, spindle cells with long thin cytoplasmic processes were found to be more in number. The measure of length and width of cell and length and width of nucleus was done. There were no significant differences in both length and width of the cell and length and width of the nucleus between 24 and 48 hours of culture condition in P1 and P2.ThesisItem Open Access REHABILITATION OF NEURO MUSCULOSKELETAL DISABLED DOGS BY SURGICAL TECHNIQUES REGENERATIVE MEDICINE, PHYSICAL THERAPY AND ORTHOPEDIC AIDS(TANUVAS, Chennai, 2017) Dar, Shahid Hussain; Jayaprakash, R.; TANUVAS; Shafiuzama, Mohamed; Sridhar, R.; Kannan, T.A.The aim of the study was to study the efficacy of different rehabilitative, therapeutic techniques in neuromusculoskeletal disabling conditions in dogs and the usefulness and effectiveness of different orthopedic aids in improving the lameness and ambulation in permanently disabled dogs. Dogs with the different disability condition of neuromuscuoloskeletal system such as patella luxation grade IV, Cranial cruciate ligament rupture, osteoarthritis and peripheral nerve paralysis and dogs with permanently disabled limbs were included in the study.OtherItem Open Access Successful Corrective Osteotomy and Rehabilitation of Angular Deformity in Two Dogs(TANUVAS, Chennai, 2016-12) Dar, Shahid Hussain; Raj, H. Pushkin; Shafiuzama, Md.; Prabha, Neelima Dasari; George, Ravi Sundar; Raidurg, RaviOtherItem Open Access Surgical Correction of Different Appendicular Tumours - A Review of 15 Cases(TANUVAS, Chennai, 2016-12) Dar, Shahid Hussain; Velavan, A.; Prabha, Neelima Dasari; Shafiuzama, Md.; Jayaprakash, R.; George, Ravi SundarOtherItem Open Access Surgical Management of Fractures in Birds - A Review of Eight Cases(TANUVAS, Chennai, 2016-12) Dar, Shahid Hussain; Raj, H. Pushkin; Gokulakrishnana, M.; Shafiuzama, Mohammed; Velaven, A.; Prabha, Neelima Dasari; Sridhar, K.; George, Ravi SundarArticleItem Open Access Surgical Removal of Ventricular Foreign Body in a Desi Chicken (Gallus Domesticus)(Indian Veterinary Journal, 2016-10) Shafiuzama, Mohamad; Babu, M.S. Sabarish; Kumar, S. Dinesh; Rao, G. Jishnu; Prabha, D. Neelima; Dar, Shahid Hussain; TANUVASA 6 month old, Desi chicken, was presented after it swallowed a safety pin. Lateral and Ventro-dorsal survey radiograph revealed the presence of a radio-opaque foreign body in the pro-ventriculus extending into gizzard. Ventriculotomy was done successfully to remove the foreign body.OtherItem Open Access Traumatic Diaphragmatic Hernia and Comminuted Femoral Fracture Post High-Rise Syndrome in a Domestic Shorthair Cat(TANUVAS, Chennai, 2016-12) Shafiuzama, Mohamed; Ali, M.G. Mohammed; Sankar, P.; Dar, Shahid Hussain; Gayathri, K.; Nair, Sindhu G.; Ashok, Chandini G.OtherItem Open Access Use of Plate-Rod Construct for the Management of Femur Fracture in Cat: A Case Report(TANUVAS, Chennai, 2016-12) George, Ravi Sundar; Shafiuzama, Mohamed; Velavan, A.; Prabha, Neelima Dasari; Dar, Shahid Hussain; Kumar, Dinesh S.