SUB-ACUTE TOXICITY STUDY OF PIROXICAM FOLLOWING REPEATED ORAL ADMINISTRATION IN WISTAR RATS”
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Date
2012
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Publisher
Anand Agricultural University, Anand
Abstract
The present study was conducted on 8-12 weeks old Wistar rats. Forty eight
(24 Male + 24 Female) rats were randomly divided into eight (I, II, III, IV, V, VI, VII
and VIII) groups. Each group consists of six animals. Group I served as male control
and group V served as female control and received only vehicle till 28 days of dosing
period. Group II, III and IV consists of 6 male animals in each group and they
received piroxicam at dose of 1, 7 and 15 mg/kg respectively orally till day 28 of
dosing period. Similarly group VI, VII and VIII consists of 6 female animals in each
and they received piroxicam at dose of 1, 7 and 15 mg/kg respectively orally till day
28 of dosing period.
All the animals were monitored throughout
Description
Keywords
Veterinary Pharmacology, Study