STUDIES ON CHEMOPROTECTIVE ACTIVITY OF PHYLLANTHUS AMARUS ON AZASERINE INDUCED PANCREATIC CANCER IN WISTAR RATS
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Date
2014
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AAU, Anand
Abstract
Eighty rats were selected for the experiment. They were randomly divided into eight groups. Group I served as a healthy control group consisted of healthy rats. Pancreatic cancer was induced in group II, III, IV, V and VI rats using azaserine as inducing agent. Group II rats were kept untreated as pancreatic cancer control. Group
“Studies on Chemoprotective activity of Phyllanthus amarus on Azaserine induced pancreatic cancer in Wistar rats”
II
III rats were treated with aqueous extract of Phyllanthus amarus (200 mg/kg body weight) and Group IV rats were treated with aqueous extract of Phyllanthus amarus (400 mg/kg body weight). Group V rats were treated with alcoholic extract of Phyllanthus amarus (200 mg/kg body weight) and Group VI animals treated with alcoholic extract of Phyllanthus amarus (400 mg/kg body weight). Group VII and VIII rats were kept as plant extract control for studying the effect of extract on normal rats.
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