“TOXICOPATHOLOGICAL STUDIES OF ACECLOFENAC IN LAYER CHICKS
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Date
2013
Authors
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Publisher
Anand Agricultural University, Anand
Abstract
The present research work was conducted on one hundred, one day old BV-300
layer chicks to study the toxicopathological effects of repeated dose (21 days) of
aceclofenac. The chicks were randomly divided into four different groups each
containing 25 chicks. Chicks of groups II to IV were given 10, 20 and 30 ppm
aceclofenac through feed for 21 days whereas, group I was kept as control. The chicks
were observed for any abnormal behavioral signs, mortality, weekly body weight gain
and feed consumption. After completion of 21 days treatment, blood samples were
collected for serum biochemical analysis from right jugular vein. The survived birds
were sacrificed by means of cervical dislocation at the end of experiment. A detailed post
mortum examination was performed on chicks which died during the experiment as well
as sacrificed at the end of the experiment and gross lesions were recorded. Tissue samples
(liver, kidney, heart, spleen, lung and intestine) were collected in 10% formalin for
histopathological examination.
The abnormal behavioral clinical signs like dullness, lethargy, lameness, anorexia
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Keywords
Veterinary Pathology, Studies