STUDY ON GENOTOXICITY OF ACEPHATE INDUCED BY REPEATED ORAL ADMINISTRATION IN WISTAR RATS

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Date
2008
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Anand Agricultural University
Abstract
Organophosphates are the most frequently used pesticides because of their rapid breakdown into environmentally safe products. Acephate, a water-soluble insecticide, belongs to the phosphoramidothioate group of organophosphate insecticides. It has moderate persistence with residual systemic activity of about 10-15 days. It is being widely used for protection of vegetables and fruits due to its activity against lepidopterans and aphids. As this insecticide is in use as crop protectant, it is likely to cause indirect exposure to animals and humans through contaminated feed, soil and water. Hence the present study was conducted to find out genotoxic potential of acephate.
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Keywords
Veterinary Pharmacology, Study
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