METABOLIC PROFILE OF CROSSBRED DAIRY COWS DURING TRANSITION PERIOD
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Date
2017
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COLLEGE OF VETERINARY AND ANIMAL SCIENCES-MANNUTHY,THRISSUR
Abstract
Dairy cows are considered to be most prone to diseases during the period
from late pregnancy to onset of lactation, i.e. during the transition period. The
present investigation was carried out in blood/serum collected at fortnightly intervals
from 15 crossbred dairy cows, from eight weeks before the predicted date of calving
till eight weeks after calving, with the objectives of generating a metabolic profile
and for evaluating the antioxidant status. Concentrations of glucose, NEFA, BHB,
cholesterol, urea, albumin, ceruloplasmin and haptoglobin were determined;
differential leukocyte count was done; and assessment of oxidative stress was also
performed. The mean concentration of glucose (47.35±1.32 mg/dL) and cholesterol
(95.83± 3.62 mg/dL) during transition period was significantly lower than pre and
post-transition period. NEFA (0.576 ± 0.08 mmol/L) and BHB (0.638 ± 0.05
mmol/L) concentrations reported significant increase during transition when
compared to pre-transition period. Concentration of indicators of protein status viz.
albumin and urea were 3.39 ± 0.09 g/dL and 12.26 ± 0.66 mg/dL respectively during
transition period and did not differ significantly from pre or post-transition period.
Out of the two acute phase proteins measured, ceruloplasmin did not show significant
variation during the study period, but a significant increase was shown by
haptoglobin during transition period. The level of MDA, an indicator of oxidative
stress was higher during transition period, indicating significant oxidative stress
during the period. TAS did not show significant change but the antioxidant status of
the animals could not be considered optimum, as eleven out of fifteen animals
exhibited diseases albeit transient during the period. A significant increase in the
number of neutrophils and monocytes and a highly significant decrease in the number
of lymphocytes observed during transition period could be due to the influence of
corticosteroids. A comprehensive study involving more number of transition
animals, maintained under different managemental conditions shall help in
establishing reference intervals for various analytes during period.
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