GROWTH AND SURVIVABILITY OF GH/Msp I GENOTYPES IN MALABARI GOATS

dc.contributor.advisorDr. k.C. Raghavan
dc.contributor.authorBINDU MATHEW
dc.date.accessioned2019-07-04T11:40:08Z
dc.date.available2019-07-04T11:40:08Z
dc.date.issued2004
dc.description.abstractGrowth hormone gene, due to its essential role in lactation and growth processes, is a perfect candidate marker associated with somatotropic axis. Selection of animals based on the growth hormone genotypes can be tntroduced in the animal husbandry sector for better production. The present investigation was undertaken to study the growth and survivability of GH/Mspl genotypes in Malabari goats at different centers of Badagara. Thalassery. Thanur as well as Malabari conservation unit. Regional Agricultural Research Station, Pilicode. DNA was isolated from 32 bucks, 241 does mated to those bucks and 297 of their progeny using phenol - chloroform extraction method. A 768-bp fragment from third exon to fifth exon containing the polymorphic Mspl site was amplified well using bovine primers, indicating species homology. The amplified product on digestion with the Mspl enzyme revealed the GWMspl {+) and (-) alleles. The percentage of incidence of (+/-) genotype was 61.76 and that of (+/+) genotype was 38.24. None of the animals typed were of the GH/Mspl (-/-) genotype. The genotype frequencies of bucks and does were consistent with the general population. In the specific heterozygous mating (+/- x +/-), 28 per cent of the progenies were (+/+) homozygotes and the rest 72 per cent were heterozygotes (+/-). Early embryonic mortality was not found to be a cause for the absence of the GH/Mspl -/- genotype as the kidding percentage in heterozygous mating were not different from other types of ma.rngs. There was no relationship between growth upto SIX months of age and G\l!Msp\ genotypes. The study conf.mrs a strong heterozygotie advantage for the GH/Mspl +/genotype and also the absenee of GH/Mspl -/- genotype in Malaban goats. Presence of duplicate copies of the growth hormone gene in goats may be a possible reason for the above results.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810111964
dc.language.isoenen_US
dc.pages57en_US
dc.publisherCollege of Veterinary and Animal Sciences, Mannuthy.en_US
dc.research.problemGROWTH AND SURVIVABILITY OF GH/Msp I GENOTYPES IN MALABARI GOATSen_US
dc.subAnimal Genetics and Breeding
dc.subjectnullen_US
dc.themeAnimal breeding and geneticsen_US
dc.these.typeM.V.Sc.en_US
dc.titleGROWTH AND SURVIVABILITY OF GH/Msp I GENOTYPES IN MALABARI GOATSen_US
dc.typeThesisen_US
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