Synthesis, characterization and microbial activity of novel schiff bases of o-phenylenediamine

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dc.contributor.advisorSharma, Sunita
dc.contributor.authorGaganpreet Kaur
dc.date.accessioned2018-02-01T09:49:33Z
dc.date.available2018-02-01T09:49:33Z
dc.date.issued2017
dc.description.abstractSchiff bases are the subject of extensive interest due to their versatile applications and similarity of structure with natural biological compounds. N- substituted benzylidene benzene-1,2-diamines (I-V) and N, N'-bis substituted benzylidene benzene-1,2-diamines (VI-X) were synthesized by reacting different aldehydes with o-phenylenediamine in the presence of catalytic amount of sodium hydroxide (10%) by taking 1:1 and 2:1 molar ratio respectively. Physical data of all the synthesized compounds was recorded. All the compounds were characterized by their IR and 1H NMR spectra and were evaluated for microbial activity against Psuedomonas sp., Klebsiella sp., Burkholderia sp. and Fusarium oxysporum. at different concentrations. The N, N'-bis substituted benzylidene benzene-1,2-diamines were found to be more effective than N- substituted benzylidene benzene-1,2-diamines. The compound VIII with halogen substitution at para position was found to be more effective than all other compounds. The other halogenated compounds followed the order Br > Cl > F. All the compounds were found to be less effective than the standard ampicillin and carbendazim (bavistin) at all the concentrations.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810040227
dc.keywordso-phenylenediamine, Schiff bases, microbial activity, Psuedomonas sp., Klebsiella sp., Burkholderia sp., Fusarium oxysporumen_US
dc.language.isoenen_US
dc.pages63en_US
dc.publisherPunjab Agricultural University, Ludhianaen_US
dc.research.problemSynthesis, characterization and microbial activity of novel schiff bases of o-phenylenediamineen_US
dc.subChemistryen_US
dc.subjectnullen_US
dc.themeSynthesis, characterization and microbial activity of novel schiff bases of o-phenylenediamineen_US
dc.these.typeM.Scen_US
dc.titleSynthesis, characterization and microbial activity of novel schiff bases of o-phenylenediamineen_US
dc.typeThesisen_US
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