Morphological And Phytochemical Investigations On St.John`s Wort (Hypericum Spp.), a Potential Source Of Ant-HIV Compounds

Simple item page
dc.contributor.advisorMini Raj, N
dc.contributor.authorGanapathy, V
dc.contributor.authorKAU
dc.date.accessioned2020-11-12T09:58:43Z
dc.date.available2020-11-12T09:58:43Z
dc.date.issued2003
dc.descriptionMScen_US
dc.description.abstractRenowned laboratories throughout the world have been makuu; uucnse search hi detect and isolate potential chemicals from plants for curing AIDS. llvpcrtcmn is :\11 important genera yielding hypericin,a potential anti -I-IIV chemical I lvpcricin ll:l~ . been reported from many exotic Hypericum species. Investigations on the presence \Ii' hypericin in the indigenous flora (H mysorense and H jU/JOl1iClIl1I) arc i:ldiJl~' I kill" the present study entitled "Morphological and Phytochemical IJl\CSII!':lllllll~ .'11 St.Johns Wort (Hypericum spp.), a potential source or anti-HI V compounds" \I;I~ constituted. Two species of Hypericum were located in Kerala; H mysorcnsc .u the high ranges of Idukki and Wayanad districts and H. japonicum in Wayanad district. The natural habitat characters of H mysorense were studied at Vattavada in IduUI Phytosociological parameters such as density, abundance and per cent frequency were determined by quatrat studies. H mysorense was often present or seldom present , along with Pteridium aquilinum, Eucalyptus grandis, Lantana camara, Strobilanthus spp, Andropogon lividis and Chrysopogon zeylanicus in the high altitucle regions of Vattavada panchayat of Idukki district Chrysopogon zeylanicus is the dominant species in the eco system. H. mysorense is a shrub with stiff branches while H japonicum is a prostrate herb growing in marshy lands. Translucent glands were either streaks or dots in H. mysorense while it was pellucid dots in H japonicum. Stem anatomy of H mysorense revealed presence of "type B" secretory canals whereas it was absent in H japonicum. Histochemical tests indicated the presence of lignin in the leaf,stem and root of H. mysorense and H. japonicum. Leaf, stem and root of H. japonicum had phenolic compounds while there was no indication for the presence of these compounds in the stem of H. mysorense. The primary metabolites like starch, total sugars,protein and total free amino acids on leaf, stem and root were quantified. Qualitative test for anthraquinone was negative in both the species. When tested using TLC for the presence of hypericin ,no spots corresponding to In \ .iluc o ! standard hypericin were observed in H. mysorense and H. japonicum samples Commercial extract of H. perforatum (EleveĀ®,) had 0.22 to 0 25 per cell! hypericin. Even though the samples of the indigenous Hypericum sP/' (//. mysorense and H. japonicum ) were negative for hypericin - the target anti-l ll V compound, they were indicative for the presence of anthronoid derivati ves. These anthronoid derivatives could be the precursors or intermediary compounds for the hypericin synthesis in the plant metabolism. These compounds need further analysis for identification and characterization for anti-HfV property.en_US
dc.identifier.citation172073en_US
dc.identifier.urihttps://krishikosh.egranth.ac.in/handle/1/5810154986
dc.keywordsPlantation Crops and Spicesen_US
dc.language.isoEnglishen_US
dc.publisherDepartment of Plantation Crops and Spices, College of Horticulture, Vellanikkaraen_US
dc.subHorticultureen_US
dc.themeMorphological And Phytochemical Investigationsen_US
dc.these.typeM.Scen_US
dc.titleMorphological And Phytochemical Investigations On St.John`s Wort (Hypericum Spp.), a Potential Source Of Ant-HIV Compoundsen_US
dc.typeThesisen_US
Files
Collections
Theses