COMPARATIVE EFFICACY OF CYANOACRYLATE TISSUE ADHESIVE AND CONTACT LENS IN MANAGEMENT OF CORNEAL ULCERS IN DOGS
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Date
2016
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COLLEGE OF VETERINARY AND ANIMAL SCIENCE-MANNUTHY,THRISSUR
Abstract
Comparative efficacy of hydrophilic soft contact lens and N-butyl-cyanoacrylate
tissue adhesive as a protective shielding in collagen gel treated corneal ulcer in dogs was
carried out in University Veterinary Hospital, Kokkalai and Mannuthy. The study was
conducted in 13 dogs with corneal ulcer, with seven and six dogs allotted to the two
treatments respectively.
Signalment and anamnesis were collected on day of presentation. Clinical
examination of dogs was conducted for evaluation of general body condition, physiological
parameters, haematological parameters, random blood sugar values, investigation for blood
parasites and detailed ophthalmic examination was performed.
Preoperatively topical and systemic antibiotics were administered to control infection
and applied Elizabethan collar to prevent self-mutilation. The patient and the affected eye
were prepared for surgery. Under general anaesthesia, superficial corneal debridement was
performed. A small amount of commercially available collagen gel impregnated with 0.1 per
cent gentamicin was applied on the ulcer bed. In seven dogs, hydrophilic contact lens was
placed over the cornea and in the remaining six dogs N-butyl-cyanoacrylate tissue adhesive
was applied over the ulcer. The eye was protected with temporary tarsorrhaphy for five days
and antibiotic therapy was continued.
Further investigation was carried out on day five, 15 and 30. Schirmer tear test,
intraocular pressure, corneal cytology, visual function test and neuro-ophthalmic test were
repeated on these days. Corneal healing was assessed by observing condition of eye, extent of
ulcer, fluorescein dye test, corneal clarity, oedema and vascularization.
Among the two treatments, the dogs treated with n-butyl cyanoacrylate had shown
earlier and recovery with least complications than those with contact lens, with regard to the
above parameters. Anyhow visual function was regained in both the groups by the end of
study, except in two cases due to corneal pigmentation.
Early contact lens loss, severe ocular discomfort, increased lacrimation, bacterial
keratitis, corneal oedema and vascularization whereas, mild ocular discomfort, increased
lacrimation and mild vascularization were the complications seen in dogs treated with contact
lens and cyanoacrylate respectively.
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