METHYLATION DETECTION IN H19 GENE IN BUFFALO (BUBALUS BUBALIS) BY BISULFITE SEQUENCING
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Date
2011
Authors
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Publisher
Anand Agricultural University, Anand
Abstract
It is increasingly clear that translation of the genetic code into proteins is not
the only way that our genes influence our growth, development and health. Another
system of influence on the expression of genes is referred to as epigenetics. Any
biochemical modification of the DNA or chromatin that can account for epigenetics
gene expression system, only one candidate mechanism that is site-specific DNA
methylation, has received experimental support to date. Methylation of DNA in
mammalian cells occurs at cytosine residues in CpG dinucleotides. Improper or
absence of DNA methylation of imprinted gene may lead to abnormal growth or
cancerous condition.
Description
Keywords
Animal Biotechnology, Study