NEUROPATHOLOGY AND DIAGNOSIS OF RABIES IN DOMESTIC ANIMALS
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Date
1996
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COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Thrissur
Abstract
An investigation was made to study the epidemiology,
clinical signs, pathologic lesions and diagnosis of rabies
in domestic animals in the state of Kerala. Epidemiology of
rabies for the last 12 year period from July 1983 to
June 1995 was assessed from the post-mortem records
maintained at the department of Pathology. Regional
distribution. Prevalence in each species and year-v/ise
occurrence were studied. Canine rabies v/as found
preponderant. Rabies was recorded in wild animals also.
Detailed clinical signs and gross pathological changes
in the rabies positive cases were .-tudied.
One hundred and six rabies suspected carcasses of
different species of animals were examined for the
disease employing Sellers' impression smear staining,
histopathology, fluorescent antibody test (FA test) and
immunoperoxidase test (IP test). Twenty-two of them were
confirmed positive for rabies.
Negribodies were demonstrated with Sellers' staining
and histopathological staining. Sellers' staining was
identified to be the simple and rapid staining method that
could be employed in the field laboratories. In addition to
H & E, Mann's stain and Sellers' stain weii "T O
staining histological sections. H & E was found to be
satisfactory for routine staining.
Histological changes in the brain (cerebrum, cerebellum
and hippocampus), salivary gland (parotid and submaxillary)
and trigeminal nerve of rabies positive animals were
studied.
The efficacy of the diagnostic techniques used for
rabies diagnosis was compared. FA test confirmed maximum
number of rabies positive cases.
The results of the rabies diagnosis was cross-checked
by Veterinary Diagnostic Laboratory, College of Veterinary
Medicine, Oregon State University, USA.
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KVASU reference style