ANTIMICROBIAL RESISTANCE PROFILING AND THERAPEUTIC STUDIES OF STAPHYLOCOCCAL PYODERMA IN DOGS
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Date
2018
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COLLEGE OF VETERINARY AND ANIMAL SCIENCES, POOKODE WAYANAD
Abstract
The present study was conducted to understand the epidemiology of canine
pyoderma, etiological agents involved, and their antimicrobial susceptibility
patterns by in-vitro antibiotic sensitivity tests, detection of antimicrobial
resistance genes and also comparison of therapeutic efficacy of CefpodoximeClavulanic acid combination and Cefovecin in treatment of staphylococcal
pyoderma in dogs.
Epidemiological investigation revealed highest incidence of Staphylococcal
pyoderma in male Labrador Retriever of 1- 3 yrs of age group. Both generalized
and localized lesions were observed. Majority of the animals brought with the
complaint of alopecia (94.37 per cent).
Clinical samples of 71 cases of canine pyoderma were subjected for culture
examination and antibiogram studies both phenotyically and genotypically.
Staphylococcus spp. was identified as the commonest organism (84.51 per cent).
Among the 60 Staphylococcus spp., 53.33 per cent were identified as S.
epidermidis followed by S. pseudintermedius (16.67 per cent), S. lugdenensis
(13.33 per cent), S. hyicus (5 per cent), S. schleiferi (5 per cent), S. aureus (3.33
per cent) and S. delphini(3.33 per cent).
On antibiogram analysis of the isolates majority showed multidrug
resistance. Penicillin resistant staphylococci were confirmed the most (62 per
cent) in the study followed by tetracycline resistance (50 per cent),
fluoroquinolone resistance (35 per cent) and Macrolide resistance (20 per cent).
Both genotypic and disk diffusion method of resistance patterns were comparable.
All the isolates were sensitive to cefovecin.
Efficacy in treatment of both the groups with Cefpodoxime-Clavulanic acid
combination and Cefovecin gave comparable response but the dogs treated with
cefovecin gave better result than other.
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