Biochemical Profile During Endotoxic Shock In Buffalo Calves (Bubalus Bubalis)
| dc.contributor.advisor | S. P. S. Singha | |
| dc.contributor.author | Neeraj Sharma | |
| dc.date.accessioned | 2019-01-10T10:02:52Z | |
| dc.date.available | 2019-01-10T10:02:52Z | |
| dc.date.issued | 2000 | |
| dc.description.abstract | Endotoxic shock has been found to occur frequently in ruminants. It causes production of free radicals, resulting in severe multifunctional organ damage. Vitamin E and selenium directly protect the cell membranes from free radical damage. The present study was undertaken to evaluate the biochemical profile during endotoxic shock and to assess the role of prophylctically supplemented Vitamin E and selenium in alleviating the endotoxic effect. Fifteen buffalo calves (6-8 months of age) were divided into three groups: Group I (Control) - infused with 0.9% normal saline; Group II - infused with E. coli endotoxin a 5 jig/kg body weight in a solution of normal saline; Group III - supplemented prophylactically with 250 mg Vitamin E and 7.5 mg selenium by intramuscular injections at weekly intervals for one month prior to induction of endotoxic shock. Endotoxin caused significant rise in activities of plasma marker enzymes, creative kinase, lactate dehydrogenase, sorbitol dehydrogenase and arginase alongwith significant hypoglycaemia, hypocholesterolaemia, hypoproteinemia, hypoalbuminernia and a different electrophoretic pattern for plasma proteins. The changes were less pronounced in animals which had received prophylactic supplementation of Vitamin E and selenium. The plasma electrophoretic protein patterns of Vitamin E and selenium supplemented group were quite similar to the normal electrophoretic patterns. The data justifies the antioxidative action of Vitamin E and selenium | |
| dc.identifier.uri | http://krishikosh.egranth.ac.in/handle/1/5810089714 | |
| dc.language.iso | English | |
| dc.publisher | Guru Angad Dev Veterinary and Animal Sciences University, Ludhiana | |
| dc.sub | Veterinary Biochemistry | |
| dc.these.type | M.V.Sc. | |
| dc.title | Biochemical Profile During Endotoxic Shock In Buffalo Calves (Bubalus Bubalis) | |
| dc.type | Thesis |
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