STUDIES ON EFFECT OF MELOXICAM ON PHARMACOKINETICS OF CEFOPERAZONE AND SAFETY OF REPEATED INTRAMUSCULAR ADMINISTRATION OF CEFOPERAZONE IN GOAT”
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Date
2011
Authors
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Publisher
Anand Agricultural University, Anand
Abstract
Cefoperazone, a new semi-synthetic third generation, piperazin β- lactam
cephalosporin, possesses broad spectrum activity against a wide range of aerobic and
anaerobic gram-positive and gram-negative bacteria. Use of non-steroidal antiinflammatory
drugs (NSAIDs) are frequently recommended with antibacterials for the
treatment of various bacterial infections accompanied by fever and other
inflammatory conditions in animals. Meloxicam, an oxicam derivative, is a
cyclooxygenase (COX) inhibitor NSAID having anti-inflammatory, analgesic and
antipyretic properties. Pharmacokinetics of an antibacterial drug may change when
administered with anti-inflammatory drug in animals.
Description
Keywords
Veterinary Pharmacology, Studies