TOXICOPATHOLOGICAL STUDIES OF ACECLOFENAC IN BROILER CHICKS”
Loading...
Date
2013
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Anand Agricultural University, Anand
Abstract
The present research work was conducted on 100 day old cobb broiler chicks to
study the toxicopathological effects of repeated dose (21 days) of aceclofenac. Broiler
chicks were randomly divided into 4 different groups each containing 25 chicks. Chicks
of group II to IV were given 10, 20 and 30 ppm aceclofenac through feed for 21 days
whereas, group I was kept as control. Clinical signs, mortality, feed intake, weight gain,
FCR, serum biochemical and pathomorphological studies were done. After completion of
21 days treatment, blood samples were collected for serum biochemical analysis from
right jugular vein. At the end of experiment, birds were sacrificed by means of cervical
dislocation. A detailed necropsy examination was performed and gross lesions were
recorded. Tissue samples (liver, kidney, lung, heart, spleen, proventriculus, gizzard,
intestine and bursa of fabricious) were collected in 10% formalin and in absolute alcohol
for histopathological examination.
During the experimnent, extent and severity of observed symptoms varied
Description
Keywords
Veterinary Pathology, Studies