TOXICOPATHOLOGICAL STUDIES OF KETOPROFEN IN BROILER CHICKS
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Date
2012
Authors
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Journal ISSN
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Publisher
Anand Agricultural University, Anand
Abstract
The present research work was conducted on 100 day old Cobb-400 broiler chicks
to study the toxicopathological effects of repeated dose (21 days) of ketoprofen. Broiler
chicks were randomly divided into 4 different groups each containing 25 chicks. Chicks
of group II to IV were given 5, 15 and 25 mg/kg b. wt. ketoprofen by oral gavage for 21
days whereas, group I was kept as control. After completion of 21 days treatment, blood
samples were collected for plasma biochemical analysis from right jugular vein. At the
end of experiment birds were sacrificed by means of cervical dislocation. A detailed
necropsy examination was performed and gross lesions were recorded. Tissue samples
(kidney, liver, heart, spleen, lung and intestine) were collected in 10% formalin solution
for histopathological examination.
The extent and severity of observed symptoms
Description
Keywords
Veterinary Pathology, Study