ASSESSMENT OF PROBIOTIC POTENTIAL AND ANTICANCER ACTIVITY OF LACTIC ACID BACTERIA ISOLATED FROM HUMAN MILK AND INFANT FECES
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Date
2020
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DEPARTMENT OF DAIRY MICROBIOLOGY SHETH M.C. COLLEGE OF DAIRY SCIENCE ANAND AGRICULTURAL UNIVERSITY ANAND
Abstract
Human milk and infant feces is considered to be a source of Lactic acid
bacteria (LAB) with promising functional attributes and technological properties and
hence a potential source of probiotics. Human milk contains several predominant
bacteria, belonging to Genera Lactobacillus, Staphylococcus, Streptococcus,
Micrococcus, Enterococcus, Lactococcus and Bifidobacterium. The bacterial flora
from the fecal samples mainly contained strains of Enterococcus faecalis,
Enterococcus faecium, Enterococcus avium, Staphylococcus
epidermidis, Lactobacillus rhamnosus, Lactobacillus fermentum, Lactobacillus
plantarum, Lactobacillus casei and Streptococcus salivarius. LAB isolated from
Human milk and Infant feces might play an important role in the prevention and
management of diseases particularly cancer and other communicable diseases. Cancer
is a significant health problem all over the world. The number of cancer patients is
expected to reach 11.5 million in 2030 worldwide. In India estimated number of
people living with the cancer is around 2.25 million. Probiotics could reduce the risk
of cancer by various mechanisms such as decreasing the bacterial enzyme activity,
suppression of the growth of microbiota concerned with the production of mutagens
and carcinogens, alteration in carcinogen metabolism, and protection of DNA from
oxidative damage as well as regulation of immune system.