SYNERGISTIC EFFECT OF ALFATOXIN B1 AND OCHRATOXIN A IN CHICK EMBRYOS
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Date
2001-04-05
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COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Thrissur
Abstract
The present study was taken up to investigate the
synergistic effects of the mycotoxins AFBl and OA on
chick embryos, the variations in the susceptibility to
the toxins both individually and in combination.
Embryomortality, teratogenicity and reduced
embryonic weight were some of the deleterious effects
observed in the inoculated chick embryos. The
abnormalities seen were more in the combined toxin
treated group and they included stunted embryos,
evisceration, herniation of yolk sac, beak
abnormalities, cranioschisis and oedema of head and
neck.
Both the liver and kidney were equally damaged and
extensive haemorrhage into the parenchyma of all the
organs was the main histological lesion observed in
addition to degenerative and necrotic changes. This
study showed that mycotoxins deleteriously affect a
number of parameters associated with embryonic growth
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