EVALUATION OF NANOCURCUMIN AND TEA WASTE EXTRACT ON EXPERIMENTALLY INDUCED CAECAL COCCIDIOSIS IN BROILER CHICKS
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Date
2016-07
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Assam Agricultural University, Khanapara, Guwahati
Abstract
The anticoccidial efficacy of three different doses of nanocurcumin (100 mg/kg bodyweight, 200 mg/kg bodyweight and 300 mg/kg bodyweight), three different doses of tea waste extract (100mg/kg bodyweight, 200mg/kg bodyweight and 300 mg/kg bodyweight) and curcumin (300 mg/kg bodyweight) were tested against Eimeria tenella infection in broilers. A total of 100 numbers of day old Broiler birds (weighing 40-50 g) were procured. All the birds were kept in deep litter system in a small group of 10 birds each. Birds were fed with standard balanced ration and clean drinking water ad libitum and were vaccinated for Ranikhet Disease at 4th day with F-strain vaccine and maintained in a standard laboratory conditions (at ambient temperature ranging between 22-25 0C). Groups 1,3,4,5,6,7,8,9 and 10 were challenged with 10,000 sporulated oocysts of E. tenella at day 10 of age, while group 2 served as the uninfected unmedicated control. Form the day of challenge infection, the birds belonging to group 3 treated with standard drug amprolium and group 4,5,6,7,8,9 and 10 were treated with different doses of nanocurcumin, curcumin and tea waste extract. From 5th day post infection, the birds showed some symptoms of diarrhoea, anorexia and weakness. From 6th day post infection, the birds started to show bloody diarrhoea, anorexia, weakness and death. A total of 22 birds died during the experiment. The negative control group (infected+untreated group) showed highest mortality (100%). The second highest mortality was found in group 7 (infected+treated with tea waste extract 100mg/kg b.w.) i.e. 40%. Other groups showed less moratlity specially the curcumin and nanocucumin treated groups. The positive control group (treated with amprolium) and group 6 (treated with nanocurcumin 300 mg/kg b.w.) showed no mortality. It was seen that Group 2 (Normal control) showed highest body weight (2260±52.64). Subsequently, Group 3 (treated with amprolium) showed a bodyweight (2175.00 ± 49.75) which has no significant difference with Group 2. Group 6 (treated with nanocurcumin300 mg) showed the highest bodyweight among the experimental groups (2015.00 ± 43.02). However, Groups treated with tea waste extract showed a significant drop in weight gain (1197.00 ± 95.37, 1106.00 ± 30.46, 1347.00 ± 30.84). Group 2 (normal control) showed highest FCR (1.64). Blood parameters were recorded and analysed and found significant difference between the groups (p<0.001). It was concluded that the effect of nanocurcumin was significantly better than tea waste extract and can be compared with the standard drug i.e. Amprolium.
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