ETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEA

Simple item page
dc.contributor.advisorK. Vinodkumar
dc.contributor.authorAMRUTHA V S
dc.date.accessioned2020-07-24T09:55:38Z
dc.date.available2020-07-24T09:55:38Z
dc.date.issued2018
dc.description.abstractNeonatal calf diarrhoea (NCD) is an economically important disease in dairy sector all over the world. Both infectious and non-infectious etiologies are reported for the disease. Major infectious etiological agents include rotavirus, coronavirus, E. coli and Cryptosporidium parvum. Present study was conducted to identify the associated risk factors, etiological agents responsible and the haemato-biochemical changes in NCD among calves reared in and around Thrissur district. Fifty diarrhoeic and twenty normal neonatal calves formed the study group. Among 50 diarrhoeic faecal samples, five were positive for Cryptosporidium spp. under acid fast staining and 19 were positive under genus specific nested PCR. Positive samples were identified as C. bovis by molecular methods. Virulence factors of pathogenic E. coli were targeted using specific primers against K99, F41, STa, intimin, Stx1 and Stx2 genes. Fifteen samples were found to possess genes for intimin, Stx1 and Stx2 together or alone as virulence factors and suggestive of the presence of EHEC/ STEC. A multi-purpose commercial sandwich antigen ELISA gave positive result for rota virus in a single sample and negative results for corona, Cryptosporidium parvum and E. coli K99 in all. Microscopic examination of faecal sample by concentration method detected the presence of ova of Strongyloid, Toxocara and unidentified nematode larvae in one sample each. Haemato-biochemical values of diarrhoeic animals when compared with normal, showed significant difference in WBC, lymphocyte count, monocyte count, serum albumin level and serum globulin levels. Since commonest pathogens found in this study are C. bovis, EAEC and EHEC in NCD, therapeutic management should aim at removal of these pathogens and correction of associated haemato- biochemical changes. Feeding of more quantities of colostrum should also be recommended.en_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810149809
dc.keywordsETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEAen_US
dc.language.isoenen_US
dc.pages82en_US
dc.publisherCOLLEGE OF VETERINARY AND ANIMAL SCIENCES-MANNUTHY,THRISSURen_US
dc.research.problemETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEAen_US
dc.subVeterinary Epidemiology and Preventive Medicineen_US
dc.subjectnullen_US
dc.themeETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEAen_US
dc.these.typeM.V.Sc.en_US
dc.titleETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEAen_US
dc.typeThesisen_US
Files
Original bundle
Now showing 1 - 1 of 1
Thumbnail Image
Name:
AMRUTHA V S.pdf
Size:
5.36 MB
Format:
Adobe Portable Document Format
Description:
ETIOPATHOLOGICAL PROFILING AND THERAPEUTIC STUDIES OF NEONATAL CALF DIARRHOEA
Download
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
1.71 KB
Format:
Item-specific license agreed upon to submission
Description:
Download
Collections
Thesis