Synthesis and antifungal potential of 1,2,4- triazolyldithiocarbamato-silver nano hybrids
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Date
2019
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Punjab Agricultural University, Ludhiana
Abstract
Sodium salts of 1,2,4-triazolyldithiocarbamates were synthesized by reacting 1,2,4-triazole/4-
amino-1,2,4-triazole with carbon disulfide under strong alkaline medium (sodium hydroxide),
which were further used for preparing other 1,2,4-triazolyldithiocarbamates(TDTC- (1-10)),
in excellent yield. Screening of synthesized compounds for antifungal potential indicated
TDTC-4 having maximum mycocidal potential against Fusarium moniliforme, Bipolaris
oryzae, Phytopathora infestans and Rhizoctonia solani better than the standard fungicides
(Tilt, Zineb and Mancozeb). Silver nanoparticles were synthesized by reduction methodology
using silver nitrate and sodium borohydride. The physiotopological properties did not allow
the significant encapsulation of compound TDTC-4 on AgNPs. So, they were not taken for
continued studies on antifungal potential.
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