EVALUATION OF PROPHYLACTIC EFFICACY OF PLANTS Boerhavia diffusa AND Tribulus terrestris ON ADENINE INDUCED CHRONIC KIDNEY DISEASE IN RATS
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Date
2020
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Department of Veterinary Medicine College of Veterinary Science and Animal Husbandry Anand Agricultural University, Anand
Abstract
The present study was conducted to evaluate the prophylactic efficacy of plants Boerhavia diffusa and Tribulus terrestris on adenine induced chronic kidney disease on 30 adult healthy male Wistar rats (12-15 weeks of age). Rats were divided into 4 groups, viz., group-I (Healthy control), II (Adenine control), III (Aqueous biherbal extract of Boerhavia diffusa and Tribulus terrestris, 0.5:1), IV (Alcoholic biherbal extract of Boerhavia diffusa and Tribulus terrestris, 1:1). Group I had 6 rats, and groups II, III and IV had 8 rats each. All the rats were numbered group wise and individually. Group I served as healthy/normal control. Group II served as adenine control, wherein adenine chemical was given @ 200 mg/kg body weight. Groups III and IV served as prophylactic treatment groups, and were given aqueous and alcoholic biherbal extracts, respectively, along with adenine solution for 28 days.