CLINICO-PATHOLOGICAL AND THERAPEUTIC EVALUATION OF PNEUMONIA IN GOATS WITH SPECIAL REFERENCE TO MYCOPLASMOSIS
Loading...
Date
2021-07-23
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Kerala Veterinary and animal Sciences University, Wayanad
Abstract
The present study on “Clinico-pathological and therapeutic evaluation of Pneumonia in goats with special reference to Mycoplasmosis” was carried out in the Department of Veterinary Clinical Medicine, Ethics and Jurisprudence, College of Veterinary and Animal Sciences, Pookode during January to December, 2020. Study group consisted of 112 goats with clinical signs like coughing, nasal discharge and abnormal breath sounds. Detailed clinical examination of respiratory system and haemato-biochemical studies were carried out. Diagnostic techniques included serological (plate agglutination test) and molecular (PCR) techniques. Standard therapeutic protocols involving Tylosin, Enrofloxacin and Oxytetracycline injections were compared in the study. The overall prevalence of caprine respiratory mycoplasmosis in goats from the present study was 84.82 per cent. Goats in the age group of < 1 year had high occurrence of respiratory mycoplasmosis. Malabari breed has the higher occurrence and the occurrence of caprine respiratory mycoplasmosis was highest during winter season. Cough, dyspnea, nasal discharge, lethargy, ocular discharge, anorexia and fever were the major clinical signs. Significant increases in RBC, WBC, neutrophils and eosinophil counts along with significant increase in values of AST and albumin were observed when comparing the hemato-biochemical values between the infected and control group. Genus specific PCR of Mycoplasma DNA yielded a specific product of 270 bp in 85 nasal swabs. Two PCR products were sent for sequencing. Sequences were analyzed in BLAST to confirm specificity of 16S rRNA gene of Mycoplasma spp. The two sequences were then submitted to the genbank and accession numbers were attained. Significant improvement in clinical condition was seen in all three drug groups. But higher rates of complete recovery in the affected goats after five days was seen in goats treated with Oxytetracycline. Hence it was inferred that Oxytetracycline was more efficient in treatment of caprine respiratory mycoplasmosis than Tylosin and Enrofloxacin.
Description
Submitted in partial fulfilment of the requirement for the degree of Master of veterinary science in Veterinary Clinical Medicine, Ethics and Jurisprudence