CHARACTERISATION OF Parteurella multocida ISOLATES FROM RABBITS
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Date
1992-09-04
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COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Trichur
Abstract
The prevalence of Pasteurella multocida in rabbits in
and around Thrissur was probed by cultural isolation and
confirmed by the elucidation of the identity of the isolates
by their physiological, biological and serological
characteristics.
A total of 112 rabbits comprising 76 apparently
healthy and 36 ailing/dead animals of various age groups and
breed were subjected to cultural screening. This attempt
fructified in the isolation of P. multocida from five rabbits
of New Zealand White breed and one of the Grey Giant breed
which died of respiratory infection. Post mortem examination
of these animals revealed typical haemorrhages in the trachea,
haemorrhages and abscessation in lungs and necrotic foci in
liver.
The present study suggests the prevalence of
P* tQ'-iba as one of the causative agent of respiratory
tract infection of rabbits kept at laboratory animals
facilities.
The biological and biochemical characters of all the
six isoj.ates were similar to those characters of rabbit
of multocida which were reported by earlier workers.
These isolates were pathogenic to mice when intraperitoneally
inoculated as all the mice were killed within
72 h. In rabbits, these isolates could not establish clinical
infection on experimental intranasal inoculation, while at
necropsy the animals revealed macroscopic and microscopic
lesions suggestive of pasteurellosis.
The antibiogram of the isolates were studied and all
the isolates were sensitive to several of the chemotherapeutic
agents but uniformly resistant to erythromycin.
Serologically/ a common somatic antigen in all the
three rabbit isolates tested and vaccine strain P^2 could be
established by gel diffusion precipitin test. However,
additional somatic antigen for one isolate and the vaccine
strain P^2 could also be detected when they were reacted
against their homologous antisera.
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