Evaluation of chronic effects of deltamethrin on Cyprinus carpio and its amelioration through dietary ascorbic acid
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Date
2007
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Publisher
CCSHAU
Abstract
The extensive use of deltamethrin a synthetic pyrethorids has led
to increase in its residue in water. The primary aim of this study was to
workout biomarkers which are measurable biological parameters that
can change in response to toxicity exposure and amelioration of toxicity
effects with in Cyprinus carpio. Sublethal dose level of deltamethrin
studied in L. cerfies for behavioural and certain hematogoical changes
with and without dietary supplement of Vitamin C ascorbic acid.
Among behavioural changes the most distinct features was increasing
exitation with increase positive in concentration as evident from the
increase in operculum movements/minutes from 63 in controls to 83 at
0.006ppm of Depetamethrin.
Among haematolgoical parameters the estimates of
haemoglobin haemato crit, total orthrocytes counts and total levocyte
count manifested significant reduction with increasing concentration of
deltamethrin upto 23.70, 23.33, 23.07 and 30.48% respectively,
likewise there have been marked decline in tissue proteins and lipids in
muscles upto 37.93 and 13.33% respectively. The total muscle
cholesterol however enhanced by 82.88% at 0.006 ppm of deltamethrin.
There were also significant changes in the activity of glycolytic enzymes
GDH & PDH showing respectively a decline up to 57.31 and 45.87%
with the increase in concentration of the pesticide. The Ascorbic acid
feeding of Ascorbic acid along with pesticide showed lesser toxicity
effects showing relatively about 8 to 10% lesser changes in
haematolgoical, Biochemical and enzymolgoical parameters. Maximum
amelioration of toxicity effects was evident in haemoglobin and PCV
contents among haematolgoical parameters and muscle cholesterols.
Later showed an improvement by 26% with ascorbic acid voer the
normal diet fed fish i.e. the cholesterol contents increased by 76.02% at
0.06 ppm with normal diet and 50.70% with ascorbic acid mixed diet.
In a pesticide concentration. This studies thus clearly evidence the
application of this haematoglocial and biochemical parameters in
assessing toxicity effects and their amelioration with ascorbic acid.
Description
Keywords
Pesticides, Acidity, Vitamins, Enzymes, Toxicity, Proteins, biological phenomena, Concentrates, Lipids, Environment