TOXICOLOGICAL STUDIES OF SHROT TERM EXPOSURE OF BANTAMIZED WHITE LEGHORN BIRDS TO ACEPHATE
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Date
2005
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Anand Agricultural University, Anand
Abstract
The present study was conducted in 8 to 10 week old Bantamized White Leghorn
birds; approximate medium lethal dose (ALD50) of Acephate use for the study was
852mg/kg. Ninety birds were divided into six different groups. The birds of group C1 was
given no treatment and served as control. Group C2 was administered groundnut oil
(1ml/kg) and served as control (vehicle). Group T1 was given 1/10th of ALD50 (85.2
mg/kg), Group T2 was put on 1/20th of ALD50 (42.6 mg/kg), while group T3 received
1/30th of ALD50 (28.4 mg/kg) and group T4 was administered with 1/40th of ALD50 (21.3
mg/kg) of Acephate suspended in 1 ml of groundnut oil. Once daily oral dosing was
carried out for 28 days. All the birds were monitored for any observable toxic symptoms
throughout the experimental period and they were also weighed weekly to monitor body
weight gain.
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Keywords
Veterinary Pharmacology, studies