MOLECULAR GENETIC STUDY OF PROLACTIN (PRL) LOCUS IN KANKREJ CATTLE AND SURTI GOAT
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Date
2007
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Anand Agricultural University, Anand
Abstract
Prolactin is a polypeptide hormone localized on
chromosome 23 and is responsible not only for triggering lactation
but also for mammary gland growth and lactogenesis in almost all
species. A silent A → G mutation in the codon for amino acid 103 in
exon 3 of bovine PRL gene gives rise to polymorphic Rsa I site and
PRL – Rsa I locus had a significant effect on milk yield and milk fat
% in dairy cattle. Therefore, the present study was undertaken with
the objectives to detect polymorphism in the prolactin gene (exon 3)
using PCR-RFLP and PCR-SSCP in Kankrej cattle and Surti goat,
both utilized as dual purpose breeds