Aflatoxin induced cytological alterations in ducks

dc.contributor.advisorManomohan, C B
dc.contributor.authorVigil Anbiah, S
dc.contributor.authorKAU
dc.date.accessioned2020-02-28T08:55:57Z
dc.date.available2020-02-28T08:55:57Z
dc.date.issued1996
dc.descriptionPGen_US
dc.description.abstractAn experimental study was conducted in desi ducks to assess the cytological alterations induced by aflatoxin Bl (AFB1) and 4 dimethyl amino azo benzene (4 DAB) One hundred and eight desi ducks of one month age were selected for the study The birds were divided into two treatment groups which were given A1 Bl (l0ug/kg body weight and l5ug/ kg body weight) and 4 DAB (5 mg and 10 mg/kg body weight) and a control group each group consisted of thirty six birds Body weight haemogram clotting time total serum protein serum albumin serum globulin albumin-globulin ratio serum aspartate amino transferase serum alanine amino transferase serum bilirubin and cytogenetic assay were estimated at periodic intervals The ducks were subjected to detailed autopsy and histopathology Clinically the exprimental birds were healthy Anaemia leucocytosis and increased blood clotting time were noticed in birds which received 15 ug/kg body weight o f AFB1 and both the dose levels of 4 DAB Total serum protein was reduced in all the treated birds In the aflatoxin group serum albumin and globulin levels were decreased Albumin globulin ratio was increased in 4 DAB tieated buds Serum aspartate ammo transferase level was elevated in buds winch moved 10ug/kg body weight of A1 Bl and 10 mg/kg body weight of 4 DAB Birds which received ATB1 as well as 10 ing/kg body weight of 4 DAB showed an elevation in serum alanine amino transferase level Serum bilirubin was incieased in all the treated birds Those ducks which were fed with AFB1 at 1 5ug/kg body weight showed tendency of hepatoma formation during the experiment The ducks which received 5 mg/kg body weight of 4 DAB exhibited gross and histopathological lesions suggestive of hepatosis and mild curhosis 1 he birds given 10 mg/kg body weight of 4 DAB tevealed gross as well as histopathological lesions of hepatic degeneiutiou and necrosis and indications of neoplatic changes Trend towaids polyploidy was the major chromosomal aberration observed in ducks which received 15g/kg body weight of AFBen_US
dc.identifier.urihttp://krishikosh.egranth.ac.in/handle/1/5810143907
dc.keywordsAflatoxin and bodyweight, Haematology, Hepatopathologyen_US
dc.language.isoenen_US
dc.publisherDepartment of Pathology, College of Veterinary and Animal Sciences, Mannuthyen_US
dc.subVeterinary Pathologyen_US
dc.subjectnullen_US
dc.themeAflatoxin induced cytological alterationsen_US
dc.these.typeM.V.Sc.en_US
dc.titleAflatoxin induced cytological alterations in ducksen_US
dc.typeThesisen_US
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