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Assam Agricultural University, Jorhat

Assam Agricultural University is the first institution of its kind in the whole of North-Eastern Region of India. The main goal of this institution is to produce globally competitive human resources in farm sectorand to carry out research in both conventional and frontier areas for production optimization as well as to disseminate the generated technologies as public good for benefitting the food growers/produces and traders involved in the sector while emphasizing on sustainability, equity and overall food security at household level. Genesis of AAU - The embryo of the agricultural research in the state of Assam was formed as early as 1897 with the establishment of the Upper Shillong Experimental Farm (now in Meghalaya) just after about a decade of creation of the agricultural department in 1882. However, the seeds of agricultural research in today’s Assam were sown in the dawn of the twentieth century with the establishment of two Rice Experimental Stations, one at Karimganj in Barak valley in 1913 and the other at Titabor in Brahmaputra valley in 1923. Subsequent to these research stations, a number of research stations were established to conduct research on important crops, more specifically, jute, pulses, oilseeds etc. The Assam Agricultural University was established on April 1, 1969 under The Assam Agricultural University Act, 1968’ with the mandate of imparting farm education, conduct research in agriculture and allied sciences and to effectively disseminate technologies so generated. Before establishment of the University, there were altogether 17 research schemes/projects in the state under the Department of Agriculture. By July 1973, all the research projects and 10 experimental farms were transferred by the Government of Assam to the AAU which already inherited the College of Agriculture and its farm at Barbheta, Jorhat and College of Veterinary Sciences at Khanapara, Guwahati. Subsequently, College of Community Science at Jorhat (1969), College of Fisheries at Raha (1988), Biswanath College of Agriculture at Biswanath Chariali (1988) and Lakhimpur College of Veterinary Science at Joyhing, North Lakhimpur (1988) were established. Presently, the University has three more colleges under its jurisdiction, viz., Sarat Chandra Singha College of Agriculture, Chapar, College of Horticulture, Nalbari & College of Sericulture, Titabar. Similarly, few more regional research stations at Shillongani, Diphu, Gossaigaon, Lakhimpur; and commodity research stations at Kahikuchi, Buralikson, Tinsukia, Kharua, Burnihat and Mandira were added to generate location and crop specific agricultural production packages.

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Subject: Veterinary Microbiology × Author: Baro, Sangeeta × End date: 2019 × Start date: 2015 × Thesis Type: M.V.Sc. ×
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    ThesisItemOpen Access
    EXPRESSION OF CERTAIN CYTOKINES IN RELATION TO PERSISTENCE OF FOOT AND MOUTH DISEASE VIRUS TYPE ‘O’ IN CATTLE
    (College of Veterinary Science Assam Agricultural University Khanapara, Guwahati-781022, 2017) Baro, Sangeeta; Sharma., K.
    The present study was undertaken to detect foot-and-mouth disease virus serotype ‘O’ in oro-pharyngeal fluid (OP fluid) and to quantify cytokines IL-1α, IL- 1β, IFN-α, TNF-α in blood of recovered animal by Real time PCR. Typing of infected clinical samples suspected for FMDV was done by sandwich ELISA followed by simultaneous detection of serotype by multiplex-PCR and detection of antibodies against NSP was done by DIVA ELISA in serum. The Relative Quantification (RQ) values for IL-1α gene during outbreak was 1.383 ±0.405 and after one month of post infection the RQ value was found to be 2.0223 ±0.592 which was found to be upregulated. Subsequently after three month of post infection the expression level of IL-1α was 23.8788±.993 which was upregulated. Later the expression level of IL-1α at 6month and nine month were 1.0223±0.299 and 1.9899±0.565 respectively. IL-1β gene expression was studied and the RQ values was found to be 0.0097±0.002 during one month of post infection which is down regulated and subsequently become undetectable during 3 month and in subsequent period of study period. The expression of IL-1β down regulation was observed in month 1 of post infection, whereas in subsequent period of the study the IL-1β was undetectable. Expression of IFN-α gene during outbreak was 1.0131±0.296. Up egulation of IFN-α in the 15 animals were found during 1, 3, 6 and 9 month respectively. The mRNA expression of TNF- α was studied and found to be upregulated during outbreak and during 1, 3, 6 and 9 month and the level of expression was 1.2361±0.362, 1.6346±0.478, 3.0521±0.893, 2.1447±0.628 and 1.3484±0.394 respectively. The present study thus supports the notion that real-time PCR is a powerful technique for reliable detection of persistent FMDV in recovered animals. The findings also indicated that IL-1α, IFN-α and TNF-α genes were gradually upregulated upto 3 months but IL-1β found to be down regulated with progression of recovery of the animals from the disease. Down regulation of the genes may be due to subside of the acute infection.