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University of Agricultural Sciences, Bengaluru

University of Agricultural Sciences Bangalore, a premier institution of agricultural education and research in the country, began as a small agricultural research farm in 1899 on 30 acres of land donated by Her Excellency Maharani Kempa Nanjammanni Vani Vilasa Sannidhiyavaru, the Regent of Mysore and appointed Dr. Lehmann, German Scientist to initiate research on soil crop response with a Laboratory in the Directorate of Agriculture. Later under the initiative of the Dewan of Mysore Sir M. Vishweshwaraiah, the Mysore Agriculture Residential School was established in 1913 at Hebbal which offered Licentiate in Agriculture and later offered a diploma programme in agriculture during 1920. The School was upgraded to Agriculture Collegein 1946 which offered four year degree programs in Agriculture. The Government of Mysore headed by Sri. S. Nijalingappa, the then Chief Minister, established the University of Agricultural Sciences on the pattern of Land Grant College system of USA and the University of Agricultural Sciences Act No. 22 was passed in Legislative Assembly in 1963. Dr. Zakir Hussain, the Vice President of India inaugurated the University on 21st August 1964.

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Author: AMBREEN, FATIMA × Start date: 2019 × Type: Thesis × Thesis Type: M.Sc ×
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    ThesisItemOpen Access
    EFFICACY OF NIGELLA SATIVA L. AS AN ANTI-HYPERCHOLESTEROLEMIC AGENT
    (University of Agricultural Sciences, GKVK, 41477) AMBREEN, FATIMA; SUNANDA, SHARAN
    Nigella sativa is an Indian spice with potential medicinal value. The fatty acid profile of Nigella sativa was assessed by Gas Chromatography, the seed contained 12.9 per cent palmitic acid, 3.2 per cent stearic acid, 56.8 per cent linoleic acid and 24.8 per cent oleic acid. The efficacy of Nigella sativa L. as antihypercholesterolemic agent was studied in an animal model. Wistar strain albino rats were assigned into three groups first was control and another two groups were experimental. The diet for control group was standard feed pellets. In experimental groups I and II 0.5 per cent cholesterol was added to the standard feed. In experimental group II, after 30 days of feeding, 45 mg of Nigella sativa per kg body weight was added. The feeding experiment was concluded on 60th day. The biochemical parameters viz. total cholesterol, triglycerides, LDL, HDL, VLDL and blood glucose levels were analyzed at initial, 30th day and 60th day of study. Reduction in total cholesterol was achieved in experimental group II over experimental group I by 27 per cent. Similar reduction in triglycerides (50 per cent), LDL (16.62 per cent), VLDL (50 per cent), HDL (46.94 per cent) and fasting blood glucose levels (1.4 per cent) were observed in group treated with 45 mg of Nigella sativa powder per kg of body weight compared to group fed with only 0.5 per cent cholesterol along with standard diet. It can be concluded that the Nigella sativa can reduce cholesterol level hence, possess hypocholesterolemic effect.