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Chaudhary Sarwan Kumar Himachal Pradesh Agriculture University, Palampur

Himachal Pradesh Krishi Vishvavidyalaya (renamed as Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya in June, 2001) was established on 1st November, 1978.The College of Agriculture (established in May, 1966) formed the nucleus of the new farm University. It is ICAR accredited and ISO 9001:2015 certified institution. The Indian Council of Agricultural Research has ranked this University at eleventh place among all farm universities of the country. The University has been given the mandate for making provision for imparting education in agriculture and other allied branches of learning, furthering the advancement of learning and prosecution of research and undertaking extension of such sciences, especially to the rural people of Himachal Pradesh. Over the years, this University has contributed significantly in transforming the farm scenario of Himachal Pradesh. It has developed human resources, varieties and technologies and transferred these to farming community enabling the State to receive the “Krishikarman award” of Govt. of India four times in row for food grain production among small states of the country. Today, the State has earned its name for hill agricultural diversification and the farming community has imposed its faith in the University.

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Subject: Veterinary Pharmacology and Toxicology × Author: Pathak, Gyan Prakash × Start date: 2014 × Type: Thesis × Thesis Type: M.V.Sc. ×
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    ThesisItemOpen Access
    STUDIES ON PROTECTIVE EFFECTS OF SEABUCKTHORN (HIPPOPHAE RHAMNOIDES) OIL IN POULTRY AFLATOXICOSIS
    (CSKHPKV, Palampur, 2014-04) Pathak, Gyan Prakash; Varshneya, C.
    The present investigation was undertaken to study the protective actions of seabuckthorn (SBT) seed oil and glucomannan (GM) in aflatoxin (AF) treated broiler chicks. A total of 210, day old broiler chicks were used for studying the growth performance, biochemical parameter and antioxidant status for the period of 4 weeks. The seabuckthorn seeds oil was collected, SBT oil was fed orally to the broiler chicks @ 0.5 ml/kg bwt. and 1.0 ml/kg bwt. GM was mixed with the feed @ 1g/ kg whereas, AF was added @ 400ppb. The AF treatment significantly (P<0.05) reduced weight gain and increased FCR. The SBT oil as well as GM significantly (P<0.05) improved the growth performance. AF treatment produced a significant (P<0.05) decrease in total serum proteins, albumin, globulin, cholesterol, triglycerides and HDL and significant (P<0.05) increase in AST, ALT, ALP, LDH and total serum billirubin. However, SBT oil as well as GM significantly (P<0.05) restored these biochemical parameters to control levels. In aflatoxin treated groups the malondialdehyde (MDA) level of liver, kidney and blood were significantly (P<0.05) increased whereas GSH, Catalase, SOD and GPx levels were significantly (P<0.05) decreased, while there was no significant (P>0.05) change in these parameters were found following only SBT oil administration. The combined dietary supplementation of SBToil+AF and GM+AF produced significant (P<0.05) decrease in lipid peroxidation and an increase GSH, catalase, SOD and GPx level of liver, kidney and blood respectively than that of AF treated groups. The histopathological lesions in the liver were severe in AF treated group and were least severe in SBToil+AF followed by GM+AF groups and there were no lesions in only SBT oil alone treated groups. On the basis of growth performance, biochemical parameters, antioxidant activity and histology of the liver tissues, it is be concluded that oral supplementation of seabuckthorn oil @ 0.5 ml/kg bwt. has provides protection against aflatoxicosis in broilers.