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Chaudhary Sarwan Kumar Himachal Pradesh Agriculture University, Palampur

Himachal Pradesh Krishi Vishvavidyalaya (renamed as Chaudhary Sarwan Kumar Himachal Pradesh Krishi Vishvavidyalaya in June, 2001) was established on 1st November, 1978.The College of Agriculture (established in May, 1966) formed the nucleus of the new farm University. It is ICAR accredited and ISO 9001:2015 certified institution. The Indian Council of Agricultural Research has ranked this University at eleventh place among all farm universities of the country. The University has been given the mandate for making provision for imparting education in agriculture and other allied branches of learning, furthering the advancement of learning and prosecution of research and undertaking extension of such sciences, especially to the rural people of Himachal Pradesh. Over the years, this University has contributed significantly in transforming the farm scenario of Himachal Pradesh. It has developed human resources, varieties and technologies and transferred these to farming community enabling the State to receive the “Krishikarman award” of Govt. of India four times in row for food grain production among small states of the country. Today, the State has earned its name for hill agricultural diversification and the farming community has imposed its faith in the University.

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Subject: Veterinary Pathology × Author: Tribhuvna × End date: 2014 × Start date: 2014 × Type: Thesis ×
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    ThesisItemOpen Access
    EFFECT OF LANTANA CAMARA ON EXPERIMENTAL SALMONELLOSIS IN JAPANESE QUAIL
    (CSKHPKV, Palampur, 2014-07-19) Tribhuvna; Asrani, R.K.
    The present study was planned with a view to observe the effects of methanolic extract of leaves of Lantana camara on growth, mortality, clinical signs, biochemical, pathological and ultrastructural changes in Japanese quail against salmonellosis. Four hundred day old Japanese quail were randomly divided into four groups and fed chick mash alone (group CX), plain chick mash with methanolic Lantana leaf extract at the rate of 4gm lts-1 of drinking water (group LX), birds challenged with S. Gallinarum (2x103 cfu ml-1) orally (group SX) and birds challenged with S. Gallinarum (2x103 cfu ml-1) orally and kept on methanolic Lantana extract (group LS). Extract water was given for 10 DPI. Results of present study showed that Salmonella infected groups exhibited clinical signs of greenish diarrhoea, anorexia, drooping of wings, ruffling of feathers, laboured and shallow breathing, huddling, restricted movement, partial closure of eyes, dullness and depression. Higher values of ALT, serum cholesterol, creatinine and total protein and lower albumin values were observed in the infected groups as compared to the control birds, however in the combination group the values were less as compared the group SX. Grossly, in the group SX hepatomegaly, splenomegaly, congestion, bronze discolouration of liver and necrosis on liver and spleen was mainly observed. However, in the combination group the gross lesions were lower as compared to group LS up to 10 DPI, but increased significantly afterwards when extract water was stopped. Microscopically, the liver of group SX revealed necrosis, increased cytoplasmic granularity, vacoular changes, leukocytic infiltration and hepatocellular and bile duct hyperplasia. Similarly in this group spleen showed necrosis, reticuloendothelial hyperplasia, heterophilic infiltration and lymphoid depletion. But the changes in the liver and spleen were less severe in the combination group. Ultrastructural changes in the group LX revealed relatively dense population of mitochondria along with abundant glycogen particles with no significant nuclear changes, but proliferation of peroxisomes was evident as compared to control. The ultrastructural changes in plain Salmonella infected group birds revealed remarkable changes in mitochondria with pleomorphism and loss of cristae, dilatation and vesiculation in the Endoplasmic reticulum, chromatin margination, dilatation of bile duct and increase in lysosomal activity and phagocytosis. However, the response in the combination group was found to be better as compared to the Salmonella alone group, which included dense population of mitochondria with no pleomorphism or loss of cristae and abundant glycogen particles and increased number of peroxisomes. These changes indicate that there was some level of hepatoprotection of the methanolic leaf extract of Lantana camara against experimental salmonellosis.