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Chaudhary Charan Singh Haryana Agricultural University, Hisar

Chaudhary Charan Singh Haryana Agricultural University popularly known as HAU, is one of Asia's biggest agricultural universities, located at Hisar in the Indian state of Haryana. It is named after India's seventh Prime Minister, Chaudhary Charan Singh. It is a leader in agricultural research in India and contributed significantly to Green Revolution and White Revolution in India in the 1960s and 70s. It has a very large campus and has several research centres throughout the state. It won the Indian Council of Agricultural Research's Award for the Best Institute in 1997. HAU was initially a campus of Punjab Agricultural University, Ludhiana. After the formation of Haryana in 1966, it became an autonomous institution on February 2, 1970 through a Presidential Ordinance, later ratified as Haryana and Punjab Agricultural Universities Act, 1970, passed by the Lok Sabha on March 29, 1970. A. L. Fletcher, the first Vice-Chancellor of the university, was instrumental in its initial growth.

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20131
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Subject: Chemistry × Author: Anil Kumar × Type: Thesis × Thesis Type: Ph.D ×
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    ThesisItemOpen Access
    Synthesis, characteriztation and bioevaluation of potential agrochemicals
    (CCSHAU, 2013) Anil Kumar; Rajvir Singh
    Heterocyclic systems find wide variety of application in agrochemicals and pharmaceuticals industries. Different organic compounds like, chalcones, coumarins, pyrazoles, isoxazoles and many other heterocyclic compounds containing functionalized nitrogen and oxygen play a predominant role in agrochemicals/pesticide chemistry. They have shown versatile biological activities and have been intensively used as scaffolds for pesticide development. Keeping all this in mind synthesis of 4-[(substituted phenyl-/phenoxy) anilinomethyl-/methyl]-2H-1-naphthopyran-2-ones, 1-[4-(substituted phenyl)-3-(substituted phenyl) prop-2-en-1-ones, 2-(substituted phenoxy)-1-(substituted phenyl) ethanones, pyrazoles, isoproterenol and flavanoids have been carried out. The synthesized compounds were characterized by 1HNMR, IR and other physical and analytical data. Compounds were evaluated for their antifungal and antibacterial activity against A. awamori and S.rolfsii and Bacillus by poisoned food technique and zone inhibition method respectively. Compounds were tested at 10μg/ml, 50 μg/ml, 100 μg/ml and 200 μg/ml. Various compounds of different series exhibited very significant antifungal and antibacterial activity. It was evident from structure activity relationship (SAR) that chloro substituent at different positions in different series of compounds showed the highest toxicity and replacement of chlorine with other functionality like methyl, methoxy bromine decrease the activity significantly. The compounds found acetone needs further exploration for their possible use as agrochemicals.