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Govind Ballabh Pant University of Agriculture and Technology, Pantnagar

After independence, development of the rural sector was considered the primary concern of the Government of India. In 1949, with the appointment of the Radhakrishnan University Education Commission, imparting of agricultural education through the setting up of rural universities became the focal point. Later, in 1954 an Indo-American team led by Dr. K.R. Damle, the Vice-President of ICAR, was constituted that arrived at the idea of establishing a Rural University on the land-grant pattern of USA. As a consequence a contract between the Government of India, the Technical Cooperation Mission and some land-grant universities of USA, was signed to promote agricultural education in the country. The US universities included the universities of Tennessee, the Ohio State University, the Kansas State University, The University of Illinois, the Pennsylvania State University and the University of Missouri. The task of assisting Uttar Pradesh in establishing an agricultural university was assigned to the University of Illinois which signed a contract in 1959 to establish an agricultural University in the State. Dean, H.W. Hannah, of the University of Illinois prepared a blueprint for a Rural University to be set up at the Tarai State Farm in the district Nainital, UP. In the initial stage the University of Illinois also offered the services of its scientists and teachers. Thus, in 1960, the first agricultural university of India, UP Agricultural University, came into being by an Act of legislation, UP Act XI-V of 1958. The Act was later amended under UP Universities Re-enactment and Amendment Act 1972 and the University was rechristened as Govind Ballabh Pant University of Agriculture and Technology keeping in view the contributions of Pt. Govind Ballabh Pant, the then Chief Minister of UP. The University was dedicated to the Nation by the first Prime Minister of India Pt Jawaharlal Nehru on 17 November 1960. The G.B. Pant University is a symbol of successful partnership between India and the United States. The establishment of this university brought about a revolution in agricultural education, research and extension. It paved the way for setting up of 31 other agricultural universities in the country.

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  • ThesisItemOpen Access
    Phytochemical analysis of some plants of family Lamiaceae and Amaranthaceae and screening of their biological activities
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2011-01) Agarwal, Ruchi; Pant, A.K.
    The essential oils of different collections of T. quadrifarium Buch.-Ham. ex D.Don from Patwadangar and Bhowali (Kumaon region) were analysed by GC and GC/MS. Analysis of T. quadrifarium essential oil from Patwadangar showed that presence of the 49 components contributing to 91.22% of the oil. The major components were E-7- caryophyllene (25.0%), copaene-4-8-ol (10.0%), caryophyllene oxide (9.5%), aromadendrene (6.3%), 8-humulene (4.2%) and germacrene-D (3.3%). The essential oil of T. quadrifarium for Bhowali showed the presence of 63 components contributing to 97.7% of the total oil. The major constituents in the oil were caryophyllene oxide (32.1%), 8-cadinol (7.2%), humulene epoxide (5.3%), 8-epi muurolol (5.3%), cadalene (5.3%), 7-selinene (5.2%), germacrene-D (4.6%) and t-cadinol (3.8%). Comparison of the results revealed that the composition of essential oil of T. quadrifarium from Bhowali collection seem to be quite different from the other collection of Patwadangar. GC-MS analysis of TMS derivative of methanol extract of T.quadrifarium revealed the presence of more than fifty components which contributed to 91.67% of the total TMS derivative. The major phenolic acids identified in the extract were salicylic acid (0.2%), syringic acid (0.1%), p-coumaric acid (0.01%) and caffeic acid (0.2%). The only phenolic acid glycoside identified in the extract was caffeoyl glycoside (0.1%). The GC and GC-MS analysis of the essential oil of Scutellaria scandens Buch.-Ham. ex D.Don revealed that the presence of the 43 components contributing to 71.4% identified component of the oil. 5-neo-cedranol (7.0%), caryophyllene oxide (6.8%), cuprene (6.7%), vaterianol (5.2%), curcuphenol (4.1%), 7-cedrene (3.5%), 3-iso-thujpsanone (2.7%), benzalacetone (2.3%), 3-thujopsanone (2.2%) and <–muurolol (2.2%) were the major components. The GC and GC-MS analysis of the essential oil of Scutellaria repens Buch.-Ham. ex D.Don showed the presence of 57 compounds, accounting for 80.95% identified component of the oil. The major components were cis-thujopsene (28.1%), 7-cedrene (5.7%), germacrene-B (4.6%), epi-8-cedranol (4.2%), >-cadinene (2.1%), 8-acoradiene (2.0%) and 7-chamigrene (1.9%). The essential oil of the Pogostemon benghalensis Kuntze resulted in the identification of 42 constitutents contributing to 73.57% identified component of the oil. The major constituents in the oil were furan eudesma-4,10 diene (32.8%), arbusbulone (10.21%), 8-yalangene (7.12%), 7-caryophyllene (7.02%), germacreone (6.23%), 1-octene-3-ol (5.02%), 7-bisabolene (4.20%), Eocimene (2.43%), elemol (2.58%), ?-bisabol-1,4-diene (1.38%), germacrene-D-4-ol (1.40%), 7-copane-48-ol (1.24%), 8-cadinol (1.51%), 7-eudesmol (1.70%), germacrene-B (2.84%), germacrene-D (1.34%) and 7-elemene (1.07%). The two components of the essential oil of Pogostemon benghalensis were separated by column chromatography. The compounds were identified on the basis of their spectroscopic data as fruan eudesma-4,10 diene and 8-cadinol. The phenolic acid and their glycosides identified in the TMS derivative of methanol extract of Pogostemon benghalensis were ferulic acid (0.04%), caffeic acid (0.1%), p-coumaric acid (0.1%), chlorogenic acid (0.5%) and caffeic acid glucoside (0.1%). Two compounds were isolated from the benzene extract of Cyathula tomentosa Moq. root (Compound I and II). 1HNMR, 13CNMR and DEPT spectra were recorded, the isolated compound I was identified as 7-sitosterol while compound II remained unidentified. The in vitro antioxidant potential of essential oils and extracts were evaluated for reducing power essay, 2’,2’-diphenylpicryl hydrazyl (DPPH) radical scavenging activity and chelating activity of Fe2+ ion. The maximum reducing power observed for essential oil of S. repens (1.220±0.00 to 1.280±0.000), followed by S. scandens (0.913±0.000 to 1.210±0.000), P. benghalensis leaf (0.753±0.000 to 1.137±0.001), P. benghalensis root (0.638±0.000 to 1.280 ±0.002) and T. quadrifarium (0.324±0.000 to 0.370±0.000) at dosage from 5 μL to 25. All the oils possess lower reducing power than standard BHT (2.302±0.000 to 2.508±0.001), catechin (4.000±0.000 to 4.000±0.000) and gallic acid (4.000±0.000 to 4.000±0.000). In methanolic extract maximum reducing power was observed for T. quadrifarium and S.scandens extract (4.000±0.000 and 4.000±0.000) respectively. The minimum reducing power was observed in extract of P. benghalensis root (0.461±0.001 to 0.612±0.000), followed by S. repens (0.367±0.00 to 0.461±0.008). The methanolic extract of flower of C. tomentosa (0.600±0.001 to 0.646±0.003) showed maximum reducing power followed by C.tomentosa leaf (0.334±0.000 to 0.483 ±0.001) and C. tomentosa root (0.200±0.000 to 0.436±0.001). All the methanolic extracts of C. tomentosa exhibited less reducing power than standards at concentration 5 mg to 25 mg. The essential oil of P. benghalensis (root) and P. benghalensis (leaf) (92.13±0.034 to 97.37±0.000 and 81.54±0.164 to 82.92±0.000) exhibited maximum DPPH radical scavenging activity. Minimum scavenging activity observed in essential oil of T. quadrifarium (43.03±0.001 to 44.29±0.000). Methanolic extract of T. quadrifarium (81.12±0.282 to 92.10 ±0.236) exhibited maximum scavenging activity and P. benghalensis (72.28±0.040 to 80.87±0.034) showed the least scavenging activity. Methanolic extract of C. tomentosa leaf (63.43±0.040 to 78.22±0.346) exhibited maximum scavenging activity followed by C. tomentosa root (56.51±0.034 to 72.33±0.800) and C.tomentosa flower (58.79±0.040 to 70.76±0.040). Essential oil of S. scandens (69.56±.001 to 78.92±.001%) showed highest chelating activity followed by T. quadrifarium, S. repens and P.benghalensis root (69.91±0.000 to 72.88 ±0.000%); (66.14±0.000 to 76.51±0.001%) and (64.87±0.040 to -70.17±0.073%). The methanolic extract of S. repens (75.67±0.150 to 87.28±0.005 %) showed maximum chelating activity followed by P. benghalensis root (73.71±0.045 to 77.63±0.005). The methanolic extract of C. tomentosa flower (83.10±0.057 to 98.24±0.098) and C. tomentosa root (87.39±0.000 to 91.24±0.040) showed more chelation in comparison to EDTA and citric acid (86.50±0.017 to 89.19±0.040 and 86.19 ±0.017 to 92.54±0.040) respectively. Biochemical assay for the different plants of family Lamiaceae revealed that all the plants were possess the total phenol more than 1mg/100, ortho dihydric phenol content also more than 1mg/100 in T. quadrifarium, P. benghalensis and S.repenes. The flavonoid contents were observed less than 1mg/100 in all species except T.quadrifarium. All the tested oils of T. quadrifarium and P. benghalensis root and extracts P.benghalensis and C. tomentosa showed anti-inflamatory, anti-nociceptive and antipyretic activities in dose dependent manner. All the oils and extracts showed reduction in inflammation but less than standard drug ibuprofen. T. quadrifarium extract showed maximum anti-nociceptive avtivity at the dose of 100 mg/kg body wt followed by C.tomentosa. The oils and extracts of P. benghalensis, T. quadrifarium and C. tomentosa produced significant (p<0.05) antipyretic effect in a dose dependent manner. None of the oils and extracts exhibited toxicity at 40, 60 and 80% and 400, 600 and 800 mg/kg concentration. Ibuprofen, indomthacin and paracetamol were taken as standard drugs for comparison.