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Govind Ballabh Pant University of Agriculture and Technology, Pantnagar

After independence, development of the rural sector was considered the primary concern of the Government of India. In 1949, with the appointment of the Radhakrishnan University Education Commission, imparting of agricultural education through the setting up of rural universities became the focal point. Later, in 1954 an Indo-American team led by Dr. K.R. Damle, the Vice-President of ICAR, was constituted that arrived at the idea of establishing a Rural University on the land-grant pattern of USA. As a consequence a contract between the Government of India, the Technical Cooperation Mission and some land-grant universities of USA, was signed to promote agricultural education in the country. The US universities included the universities of Tennessee, the Ohio State University, the Kansas State University, The University of Illinois, the Pennsylvania State University and the University of Missouri. The task of assisting Uttar Pradesh in establishing an agricultural university was assigned to the University of Illinois which signed a contract in 1959 to establish an agricultural University in the State. Dean, H.W. Hannah, of the University of Illinois prepared a blueprint for a Rural University to be set up at the Tarai State Farm in the district Nainital, UP. In the initial stage the University of Illinois also offered the services of its scientists and teachers. Thus, in 1960, the first agricultural university of India, UP Agricultural University, came into being by an Act of legislation, UP Act XI-V of 1958. The Act was later amended under UP Universities Re-enactment and Amendment Act 1972 and the University was rechristened as Govind Ballabh Pant University of Agriculture and Technology keeping in view the contributions of Pt. Govind Ballabh Pant, the then Chief Minister of UP. The University was dedicated to the Nation by the first Prime Minister of India Pt Jawaharlal Nehru on 17 November 1960. The G.B. Pant University is a symbol of successful partnership between India and the United States. The establishment of this university brought about a revolution in agricultural education, research and extension. It paved the way for setting up of 31 other agricultural universities in the country.

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  • ThesisItemOpen Access
    Studies on the effects of tiletamine-zolazepam, propofol and sevoflurane anaesthesia in dexmedetomidine and butorphanol premedicated dogs
    (G.B. Pant University of Agriculture and Technology, Pantnagar, District Udham Singh Nagar, Uttarakhand. PIN - 263145, 2022-07) Tiwari, Kanika; Jadon, Narendra Singh
    Thirty-six adult dogs used in the study were randomly divided into 6 subgroups (A-1, A-2, A-3, B-1, B-2 and B-3). All the dogs were administered with atropine sulphate at the dose rate of 0.04 mg/kg body weight subcutaneously. After five minutes, animals of group A-2 and B-2 were premedicated with dexmedetomidine whereas animals of group A-3 and B-3 were premedicated with dexmedetomidine and butorphanol at the dose rate of 5 μg/kg body weight and 0.1 mg/kg body weight intravenously. The animals of groups A-1, A-2, A-3, B-1, B-2 and B-3 induced with tiletamine-zolazepam and propofol at the dose rate of 6.66±0.06 mg/kg iv, 1.86±0.11 mg/kg iv, 1.26±0.02 mg/kg iv, 5±0.06 mg/kg iv, 2.56±0.01 mg/kg iv and 2.16±0.01 mg/kg iv respectively. Anaesthesia was maintained with sevoflurane and MAC of sevoflurane was determined by tail clamp method in all the animals. The level of anaesthesia was determined by observing various clinical (induction time, duration of anaesthesia, muscle relaxation, pedal reflex, palpebral reflex, analgesia, recovery time, sternal recumbency time, standing time, complete recovery time, required doses of induction agents and reduction in the % MAC of sevoflurane, physiological and haemodynamic (rectal temperature, heart rate, respiration rate, blood pressure, haemoglobin oxygen saturation (SpO2), electrocardiography), haematological (haemoglobin, total erythrocyte count, total leucocyte count, differential leucocyte count) and biochemical (serum glucose, total protein, serum albumin, serum urea nitrogen, serum creatinine, alanine amino transferase, aspartate amino transferase) parameters. Clinical efficacy of the anaesthetic combination was determined by performing various surgical operations.The mean induction time reduced in the animals of groups A-2, A-3, B-2 and B-3 after the administration of preanaesthetic drugs whereas longer duration of anaesthesia, recovery time, sterna recumbency time, standing time and complete recovery time were observed in the animals of group A-2, A-3, B-2 and B-3 after the administration of preanaesthetic drugs. Adequate muscle relaxation and excellent analgesia was observed in the post-induction period in all the animals of different groups. Pedal and palpebral reflexes were very weak after the induction with tiletamine-zolazepam in group A-1, A-2 and A-3 whereas it was completely lost after the induction with propofol in group B-1, B-2 and B-3. Preanaesthetic administration of dexmedetomidine and butorphanol reduced the induction dose of drugs (propofol and tiletamine-zolazepam) and MAC of sevoflurane. The rectal temperature, heart rate and respiration rate showed significant decrease at various time interval and reached to the baseline values by 24 hours post-anaesthesia. SAP, DAP and MAP was decreased non-significantly in group A-1 and B-1 whereas it showed a significant increase in group A-2, A-3, B-2 and B-3 at respective time interval. Significant decrease in haemoglobin oxygen saturation was observed after administration of induction agents. Significant reduction in PR interval was observed in animals of group A-1 whereas non-significant changes were observed in QRS and QT interval in all the groups of animals. Inverted T-wave and sinus dysrhythmia were observed after administration of dexmedetomidine whereas sinus tachycardia was observed after induction with tiletamine-zolazepam. Transient changes within physiological limits were observed in haemato-biochemical parameters which reached to baseline values by 24 hours. On the basis of above mentioned parameters, it was observed that the anaesthetic combinations used in the study have least deleterious effects on different body systems and the most efficacious anaesthetic combination was atropine sulphate-dexmedetomidine-butorphanol-tiletamine-zolazepam-sevoflurane