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Govind Ballabh Pant University of Agriculture and Technology, Pantnagar

After independence, development of the rural sector was considered the primary concern of the Government of India. In 1949, with the appointment of the Radhakrishnan University Education Commission, imparting of agricultural education through the setting up of rural universities became the focal point. Later, in 1954 an Indo-American team led by Dr. K.R. Damle, the Vice-President of ICAR, was constituted that arrived at the idea of establishing a Rural University on the land-grant pattern of USA. As a consequence a contract between the Government of India, the Technical Cooperation Mission and some land-grant universities of USA, was signed to promote agricultural education in the country. The US universities included the universities of Tennessee, the Ohio State University, the Kansas State University, The University of Illinois, the Pennsylvania State University and the University of Missouri. The task of assisting Uttar Pradesh in establishing an agricultural university was assigned to the University of Illinois which signed a contract in 1959 to establish an agricultural University in the State. Dean, H.W. Hannah, of the University of Illinois prepared a blueprint for a Rural University to be set up at the Tarai State Farm in the district Nainital, UP. In the initial stage the University of Illinois also offered the services of its scientists and teachers. Thus, in 1960, the first agricultural university of India, UP Agricultural University, came into being by an Act of legislation, UP Act XI-V of 1958. The Act was later amended under UP Universities Re-enactment and Amendment Act 1972 and the University was rechristened as Govind Ballabh Pant University of Agriculture and Technology keeping in view the contributions of Pt. Govind Ballabh Pant, the then Chief Minister of UP. The University was dedicated to the Nation by the first Prime Minister of India Pt Jawaharlal Nehru on 17 November 1960. The G.B. Pant University is a symbol of successful partnership between India and the United States. The establishment of this university brought about a revolution in agricultural education, research and extension. It paved the way for setting up of 31 other agricultural universities in the country.

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  • ThesisItemOpen Access
    Evaluation of antioxidative and immunomodulatory potential of Trigonella foenum graecum against imidacloprid induced toxicity in rats
    (G.B. Pant University of Agriculture and Technology, Pantnagar - 263145 (Uttarakhand), 2021-01) Naveen Kumar; Ahmad, A.H.
    The study was carried out to investigate the ameliorating potential of Trigonella foenum graecum in combating imidacloprid induced immunotoxicity and oxidative stress in adult male Wistar albino rats. Rats were divided into five groups of eight rats each. In group I, vehicle (olive oil), group II, imidacloprid @ 170 ppm, group III, aqueous extract of seeds of Trigonella foenum graecum alone @ 12000 ppm, group IV imidacloprid @ 170 ppm and diosgenin @ 2400 ppm, and group V, imidacloprid @ 170 ppm and aqueous extract of Trigonella foenum graecum @ 12000 ppm were administered daily with feed to the rats orally for 90 days.The results of qualitative phytochemical analysis revealed presence of alkaloids, saponins, flavonoids, phenolic compounds and carbohydrates. The DPPH and ABTS radical scavenging assays for aqueous extracts were also found to be highest in seed extract. The rate of gain in body weight was significantly decreased in imidacloprid group, however, in combination with fenugreek and diosgenin it was restored to normal level. Imidacloprid exposure caused significant increase in serum level of ALT, AST, ALP and creatinine activities as compared to all other groups. Treatment with imidacloprid significantly decreased the RBC, Hb, PCV values and was significantly lower than either of the treatment. Imidacloprid produced toxicity in the form of enhanced lipid peroxidation and reduced GSH, SOD and catalase levels. Trigonella foenum graecum was significantly effective in restoration of these parameters towards normal. ROS generation was significantly increased following exposure to imidacloprid as compared to control. Significant (p<0.05) improvement in these parameters were observed in groups where imidacloprid along with fenugreek and diosgenin was administered. Total immunoglobulin, immunoglobulin G and foot pad thickness were significantly increased in imidacloprid group in comparison to co-treatment groups of imidacloprid with fenugreek and diosgenin control group. Thepresent study summarizes that the aqueous extract of Trigonella foenum graecum seeds and diosgenin exert ameliorative effects on imidacloprid induced toxic effects which may attribute to their antioxidative and immunomodulatory properties.