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Kerala Veterinary and Animal Sciences University, Wayanad

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  • ThesisItemOpen Access
    IMMUNE RESPONSE TO COMBINED FOOT AND MOUTH DISEASE, HAEMORRHAGIC SEPTICAEMIA AND BLACK QUARTER VACCINE AND THEIR RESPECTIVE MONOVALENT VACCINES IN CATTLE
    (COLLEGE OF VETERINARY AND ANIMAL SCIENCES-MANNUTHY,THRISSUR, 2001) RAJKUMAR, K.
    Immune response to combined Foot and Mouth Disease, Haemorrhagic Septicaemia and Black Quarter vaccine and to their respective individual vaccine were studied. Group I animals were vaccinated with combined FMD, HS and BQ oil adjuvant vaccine. Group II animals were vaccinated with FMD polyvalent oil adjuvant vaccine and combined HS, BQ gel vaccine. Group III animals were vaccinated with polyvalent FMD oil adjuvant vaccine, HS gel vaccine and BQ gel vaccine. Vaccinations were done in unvaccinated calves above four month of age. Booster vaccination were carried out after nine month after primary vaccination for oil adjuvant vaccine and six month after primary vaccination for gel vaccine in all group animals. Monthly assessment of antibody titres against O, A, C and Asia-1 antigens were made by liquid phase blocking ELISA and Pasteurella multocida and Clostridium chauvoei by Indirect ELISA. All the three groups maintained protective antibody titre for FMD virus type 'O', 'A', 'C^ 'Asia-1', Pasteurella multocida and Clostridium chauvoei antibody litres throughout the study period. All the three groups did not show any significant variation in antibody litres against FMDV type, 'O', 'A', 'C and 'Asia-l'and Pasteurella multocida and Clostridium chauvoei though they are well above protective litres. From this observation it is concluded that 1. All the three schedule of vaccination provides sufficient protective litre for FMDV type, 'O', 'A', 'C and 'Asia l'and Pasteurella multocida and Clostridium chauvoei though they are well above protective litres. 2. Combined vaccine performance is equally good as that of individual vaccine. 3. Combined vaccine reduces labour cost for injection, number of visit and stress to the animals to a very great extent. There fore combined vaccine may be preferred when compared to individual vaccine.
  • ThesisItemOpen Access
    SEROCONVERSION OF THREE DIFFERENT FOOT-AND-MOUTH DISEASE VACCINES IN CATTLE
    (COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Thrissur, 2001-04-11) BIPIN., K. C.; Tresamol, P.V.
    Seroconversion of three different commercial inactivated quadrivalent Foot-and-Mouth disease vaccines were studied. One aluminium hydroxide gel vaccine and two oil-adjuvanted vaccines were used for the study in three groups of cattle. Monthly assessment of antibody titres against O, A, C and Asia-1 antigens were made by liquid phase blocking-ELISA (LPB-ELISA). Unvaccinated calves of four months and above age were grouped into three and vaccinations were made as per manufacturer's regime. Group I and group II animals did not showed significant difference m type O antibody titres throughout the study period except following booster vaccination of group I in seventh month. Both groups mamtained protective titres except in the fourth and fifth months of study. Group III showed a lower level of antibody titres throughout the study period. Protective type A antibody titres were maintained by group I and group II animals during the entire study period except in the fifth month. No significant difference between these two groups observed except following the second booster vaccination in group II. Group III showed comparatively lower antibody titres against type A FMD antigen. All the three groups showed protective mean type C antibody titres throughout the study period. But group III showed an antibody titre below protective level during fourth month. Group I and group II did not show significant variation in antibody titres except following respective booster vaccinations. Group I and group II maintained a protective level of type Asiarl antibody titres except during fifth month. Group III showed significantly low Asia-1 antibody titres throughout the study period. The booster vaccinations produced anamnestic response in group I and group II in almost all cases. Group III animals showed lower antibody titres against all the four virus types when compared to group I and group II and response to booster vaccinations were poor m group III. Comparison between the three vaccines in terms of cost required for immunising a single ammal for the first one year revealed that oil-adjuvanted vaccine II required the lowest cost while oil-adjuvanted vaccine III required the highest cost for the first one year.
  • ThesisItemOpen Access
    SEROPREVALENCE OF INFECTIOUS BOVINE RHINOTRACHEITIS IN CROSSBRED CATTLE OF KERALA
    (COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Thrissur, 2001-04-26) RAJESH, J. B.; Tresamol, P.V
    Seroprevalence of IBR in 719 crossbred cattle of Kerala was studied using Avidin-Biotin ELISA. Sera samples were collected from cattle belongmg to different places of Kerala covermg all the districts. Samples were collected randomly from cattle of different age, managemental practice, breed, sex, panty, different health status and also from different farms. Samples were subjected to Avidin-Biotin ELISA for detecting antibodies against BHV-1 infection. Out of 719 sera samples tested 14.88 per cent gave positive result for BHV-1 antibodies. Animals reared under rural farming system showed high seropositivity (18.75%) to BHV-1 infection than animals under organised farms. Seroprevalence of BHV-1 antibodies was more in animals with some history of disease (22.6%) than apparently healthy animals. This result is highly significant (P<0.01). Prevalence of BHV-1 antibodies is found to be more in crossbred cattle when compared to non-descript cattle. Seroprevalence of IBR m various age group revealed that percentage of positiveness to BHV-1 was more m animals above three years of age. Serological evidence of IBR is very less in younger animals. Also animals after one panty and above had a high percentage of seroprevalence than heifers and calves. Animals from different farms were tested for antibodies against BHV-1 infection. Private farms had a high seroprevalence of IBR infection than University farms and Government farms. There is significant difference between private farms and other farms. Seroprevalence of IBR among cattle with different clinicalmanifestations were tested. High percentage of seroprevalence noted in respiratory form of infection (33.33%). Seroprevalence of IBR m crossbred cattle of Kerala detected as 14.88%. MO HI
  • ThesisItemOpen Access
    PREVALENCE, HAEMATOLOGY AND TREATMENT OF STRONGYLOSIS IN GOATS
    (COLLEGE OF VETERINARY AND ANIMAL SCIENCES Mannuthy - Thrissur, 2001-04-27) ARUN SHAJU., T.; Saseendranath, M.R
    Prevalence of strongylosis in goats were studied by examining 782 faecal samples collected during June 1999 to June 2000. Strongylosis was present in 283 (36.19 per cent) goats. No seasonal influence on the prevalence of strongylosis was observed. Similarly infections with Strongyhides, Trichuris, Moniezia and Eimeria were also found in all seasons Kaiparamba panchayat of Thrissur district recorded the highest prevalence for strongylosis. I' A significant decrease (P<0.01) in the incidence of caprine strongylosis in University goat and sheep farm, Mannuthy was noticed dunng June 2000, when compared to June 1999. No influence of sex was observed on the prevalence of strongylosis m goats. Haematological examination of strongyle infected goats, revealed a significant change (P<0.05) m the mean values of PCV and eosmophils, when compared to that of control goats Levamisole given orally, was found most effective (100 per cent) while Closantel was least effective (86.17 per cent) against naturally occurring strongylosis in goats. Oral Levamisole was found superior to parenteral Levamisole m efficacy against caprine strongylosis in goats.