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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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20142
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Subject: Veterinary Parasitology × Start date: 2012 × Type: Thesis × Thesis Type: Ph.D ×
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    ThesisItemOpen Access
    COMPARATIVE EFFICACY OF COCCIDIOSTATS ON EXPERIMENTALLY INDUCED EIMERIA TENELLA INFECTION ALONG WITH EFFECTS ON GROWTH HAEMATO-BIOCHEMISTRY AND PATHOLOGY IN BROILERS
    (AAU, Anand, 2014) HIRANI, NITINKUMAR DEVRAJBHAI; Hasnani, J. J.
    The efficacy of three commonly used feed coccidiostats named Diclazuril (T1) Salinomycin (T2), Diclazuril + Salinomycin (T3) in shuttle programme and Maduramicin (T4) on experimentally induced Eimeria tenella coccidial infection and their effects on growth, haematology, biochemical and histopathological changes were undertaken in three hundred Cobb400 strain of broiler at University Poultry Complex, Anand Agricultural University, Anand during year 2012. Birds were given feed containing Diclazuril (T1), Salinomycin (T2), and Maduramicin (T4) coccidiostats at dose rate of 1 ppm, 60 ppm and 5 ppm upto 42 days. Weekly body weight and feed consumption were recorded. Various parameters considered for comparative efficacy were studied. Experimental infection of 50,000 oocysts of E.tenella was given on 22nd day of age. Blood was collected before experimental infection at 3 weeks and after experimental infection at 4 weeks of age for haemato-biochemical study. The results of faecal score, oocyst per gram (OPG), lesion score, oocyst index value and mortality indicated better efficacy of coccidiostats as compared to non medicated birds in experimental infection with better efficacy of Maduramicin and Salinomycin as compare to Diclazuril and Diclazuril + Salinomycin shuttle treatment. Coccidiostats proved to have growth promoting action in broiler chickens during the experimental infection. Birds fed with Maduramicin medicated (5 ppm) performed well in terms of live weight gain and feed conversion ratio and it was followed by salinomycin (60 ppm) for weight gain and Diclazuril (Ippm) for feed efficiency in broiler birds. Result of sensitivity against E. tenella indicated good efficacy of Maduramicin (82%), whereas limited efficacy of Salinomycin (76%), Diclazuril (74%) and Diclazuril + Salinomycin Shuttle group (71%)) on the basis of Global index value (GINNC % ) Haematological studies revealed that haemoglobin concentration, packed cell' volume and total erythrocytes counts were significantly (P < 0.05) reduced, while total leukocytes counts were significantly increased on account of coccidial infection in all coccidiostat treatment and infected non treated groups. Different Leukocytes Count (DLC) value revealed significant increase in heterophills, lymphocytes and eosinophills and significant decrease in monocytes and basophills on account of coccidial infection. Results on haematological studies indicated comparatively less pathological damage by Salinomycin. Studies on biochemical profile revealed significantly (P < 0.05) lower serum glucose and serum total protein, while significant increase in serum total cholesterol. Serum Glutamic Oxalo-acetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT) and Alkaline Phosphatase (AKP) activities was observed due to coccidial infection as compared to pre infection levels in birds. Results of biochemical studies indicated comparative less pathological damage by coccidiostats treatment as compared to infected non treated group, but there was no consistent trend for drug choice. From histopathological study it was clear that the Maduramicin and Salinomycin treated group showed very less mechanical damage to tissue hence it could be used as a curative remedy against the caecal coccidiosis. The presence of clusters of large schizonts in the caecum was pathognonomic for E. tenella. The magnitude of infection type and dose of coccidiostat and stage of development of the disease could be established by histopathological observation.
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    ThesisItemOpen Access