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Anand Agricultural University, Anand

Anand Agricultural University (AAU) was established in 2004 at Anand with the support of the Government of Gujarat, Act No.(Guj 5 of 2004) dated April 29, 2004. Caved out of the erstwhile Gujarat Agricultural University (GAU), the dream institution of Sardar Vallabhbhai Patel and Dr. K. M. Munshi, the AAU was set up to provide support to the farming community in three facets namely education, research and extension activities in Agriculture, Horticulture Engineering, product Processing and Home Science. At present there seven Colleges, seventeen Research Centers and six Extension Education Institute working in nine districts of Gujarat namely Ahmedabad, Anand, Dahod, Kheda, Panchmahal, Vadodara, Mahisagar, Botad and Chhotaudepur AAU's activities have expanded to span newer commodity sectors such as soil health card, bio-diesel, medicinal plants apart from the mandatory ones like rice, maize, tobacco, vegetable crops, fruit crops, forage crops, animal breeding, nutrition and dairy products etc. the core of AAU's operating philosophy however, continues to create the partnership between the rural people and committed academic as the basic for sustainable rural development. In pursuing its various programmes AAU's overall mission is to promote sustainable growth and economic independence in rural society. AAU aims to do this through education, research and extension education. Thus, AAU works towards the empowerment of the farmers.

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2005 - 200932010 - 201723
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Subject: Veterinary Parasitology × End date: 2019 × Start date: 2000 ×
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Now showing 1 - 9 of 26
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    ThesisItemOpen Access
    STUDIES ON HELMINTHIC INFECTION IN HORSE (Equus caballus)
    (DEPARTMENT OF VETERINARY PARASITOLOGY COLLEGE OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY ANAND AGRICULTURAL UNIVERSITY ANAND, 2017) Prakriti Singh; Dr. P. V. Patel
    The study was carried out to ascertain the monthwise, seasonwise, agewise, sexwise, breedwise, and overall prevalence as well as haematological and biochemical aspects of gastrointestinal helminthosis in horses at Anand District of Gujarat. The study was undertaken for the period of twelve months from March-2016 to February-2017. The faecal samples were collected from the horses brought to the Veterinary Clinical Complex (VCC), Department of Surgery and Radiology, College of Veterinary Science and A. H., AAU, Anand and the surrounding field areas. For recording and findings of prevalence, faecal samples of horses were collected for the detection and identification of eggs of gastrointestinal helminths as per standard method.
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    ThesisItemOpen Access
    STUDIES ON PREVALENCE, HAEMATOBIOCHEMICAL ALTERATIONS AND DIAGNOSTIC ASPECTS OF Trypanosoma evansi USING ADVANCED MOLECULAR TOOL AND BLOOD SMEAR EXAMINATION IN CATTLE AND BUFFALOES
    (COLLEGE OF VETERINARY SCIENCE AND ANIMAL HUSBANDRY ANAND AGRICULTURAL UNIVERSITY ANAND, 2017) Suchit S. Pandya; Dr. J. J. Hasnani
    In the present study, the prevalence of Trypanosomosis in cattle and buffaloes was studied by examination of blood samples collected from Anand and Mahisagar districts, Gujarat during the period from January 2016 to December 2016. Blood smear examination was done using microscope (100x) and stained with giemsa’s. A total of 502 and 495 blood samples of cattle and buffaloes were collected from Anand and Mahisagar districts and of which 66 (13.33%) and 42 (8.16%) samples were found positive for Trypanosoma evansi, respectively. The highest prevalence rate was observed in the month of September 11.94% and lowest in April 0.0% whereas the, highest prevalence was recorded in the month of October 20.63 % and lowest in April 4.76 % for cattle and buffaloes from Anand and Mahisagar districts, Gujarat. It was also observed that, occurrence of infection was increased from June up to the month of February except in November in cattle and buffaloes where it was decreased and from March onwards occurrence of the infection was decreased up to the month of June.
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    ThesisItemOpen Access
    Transcriptome Analysis of Paramphistomum cervi of water buffalo (Bubalus bubalis) using next generation sequencing
    (AAU, Anand, 2013) CHOURASIA, REETIKA; PATEL, P. V.
    Rumen flukes are economically important parasites (Platyhelminthes: Trematoda: Digenea) that attack livestock adversely thereby affecting their productivity. In spite of its economic importance, molecular biology of the Paramphistomum cervi and its interaction with its hosts is still unknown. Advances in transcriptomic and bioinformatics provide biologically relevant insights into parasites, their developmental stages and their relationships with their hosts at the molecular level. The present study elucidates the first transcriptome and gene expression profiling of the adult stage of Paramphistomum cervi using next-generation (high throughput) sequencing and advanced in silico analyses. Expression level for predicted proteins of Paramphistomum cervi of buffalo were determined and classified based on homology, gene ontology and pathway mapping. These findings are expected to provide new insights into the genetic architecture and pathophysiology of Paramphistomum cervi and for the development of improved interventions for disease control. It will also facilitate a more fundamental understanding of Paramphistomes biology, evolution and the host-parasite interplay. Moiphological characteristics of adult fluke were identified as conical shape, elongate, curved ventrally, with evenly curved dorsal and ventral borders. Cuticle is provided with prominent tubercules/papillae on anterior l/3rd to half of the body. Tubercles are more extensive ventrally. Acetabulum is subtemiinal. hitestinal caeca have 7 nearly identical bends with ventrally directed temiinal part. Testes are tandem, oval or angularly oval or spherical and are deeply lobed. Gross examination of affected rumen showed, anaemic rumen with atrophied, degenerated and sloughing tips of villi. Removal of flukes revealed marked knobs at the attachment sites. Histopathology of rumen revealed proliferation of epithelium in the vicinity of flukes, along with villous atrophy and infiltration of macrophages and eosinophils. Transcriptome analysis of adult stage of Paramphistomum ceni was carried out at Department of Animal Biotechnology. Total RNA was extracted from parasites using TRIzol® (Invitrogen, UK)/ RNeasy® mini kit and mRNA isolation from the total RNA was carried out by using mRNA isolation kit. The quality and quantity of RNA and mRNA checked by running the sample on NanoDrop ND-1000 spectrophotometer. Concentration of RNA of adult fluke was 2,608 ng/µl and mRNA was 100 ng/µl. The cDNA library was constructed using the Ion Total RNA-Seq Kit v2. According to Qubit®Fluorometer, concentration of cDNA was 1.19 ng/µl and based on Aligent 2100 Bioanalyzer concentration of cDNA is 1.25 ng/µl.
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    ThesisItemOpen Access
    STUDIES ON GASTRO-INTESTINAL PARASITES OF POULTRY IN ANAND DISTRICT
    (AAU, Anand, 2012) Gupta, Yogesh Kumar; Hasnani, J. J.
    Studies on prevalence of GI parasites on commercial poultry farms under deep litter and cage system of housing with it's effect on haemato-biochemical profile and histopathology were imdertaken during July 2011 to June 2012. Studies involved 600 birds dropping, 30 carcasses and 100 blood samples from 30 Commercial layer and broiler farms in 6 talukas of Anand district. The overall prevalence of GI parasites on the farm basis was found 46.67 % m 30 farms of 6 taluka. Out of these overall taluka-wise prevalence was found 20% in layer farms, while 26.67% in broiler farms. However, incidence was lowest overall and among the farm and bird basis in Anand taluka, while it was highest in Umreth and Petlad taluka. Among the layers, lower incidence was observed on birds-basis in Anand and highest in Borsad taluka. The overall prevalence was found higher in deep litter than the cage reared birds/farms and also in broilers as compared to layers. The overall prevalence of gastrointestinal parasitic eggs/oocyst in chickens in commercial layer as well as broiler was 9.17% on the basis of faecal/litter dropping among 600 samples. Out of these 7.67% prevalence was in layers and 10.67% in broilers. The prevalence of GI parasitic infection was higher in overall poultry birds during monsoon season (12.50%), followed by winter season (8.50%), and summer (6.50%), whereas month-wise prevalence was found to be the highest in the month of July (17.07%), while lowest incidence was found in the month of April (5.66%). A total of 4 species of gastrointestinal parasitic eggs/oocyst were identified. All of these Coccidia were the most predominant parasites followed by nematode and cestodes. The following Parasitic eggs/oocysts were found in layer birds: Eimeria spp. (3.33%), Ascaridia galli (1.33%) and Heterakis gallinarum (0.67%). some cestodes identified were: Raillietina spp. (2.33%). The following Parasitic eggs/oocysts were found in Broiler birds: Eimeria spp. (4.33%), Ascaridia galli (3.33%)), Heterakis gallinarum (1.33%) and Raillietina spp. (1.67%). No significant differences in the intensity of endoparasitic infection was observed between broiler and layer chickens. Among the layer birds the prevalence of GI parasites in the age group of 0-8, 9-20 and 21-72 weeks was 1.33, 4.67 and 1.67 %, respectively on the basis of faecal samples examination. The findings revealed that the incidence was highest in the age group of 9- 20 weeks, lowest in the age group of younger birds of 0-8 weeks and intermediate in the 21-72 weeks age group on the basis of faecal samples examination. Among the broiler birds, the prevalence of GI parasites was found to increase gradually with the advancing age from 1-4 weeks in the range of 4.00% and 5-6 weeks was 6.67 %, respectively. Overall incidence was higher for broiler birds in the age group of 5-6 weeks as compared to those in 1-4 weeks. Haematological studies revealed the haemoglobin concentration and packed cell volume significantly lower in GI parasitic infected group compared to the healthy groups of birds (9.02±0.13 vs 10.93±0.20 gm% and 24.83±0.28 vs 31.60±0.31%) irrespective of type of birds or system of rearing; where as total leucocytes count and different leucocytes count were increased significantly. The overall mean total leucocytes count (TLC) for the healthy and infected group of birds was 28.58±0.22 and 31.74±0.32 thousand/mm^, respectively. In overall GI parasitic infected cases, heterophils were significantly (P< 0.05) higher (41.82±0.19%) when compared with that of uninfected (37.13±0.25%) birds. The percentage of lymphocytes (34.03±0.20) were significantly (P<0.05) lower in overall helminths affected birds than uninfected (47.26±0.33) birds. Statistical analysis revealed significant (P<0.05) eosinophilia (13.03±0.21%) in GI parasitic infected birds. The average percentage of eosinophils in uninfected birds was 7.82±0.17. The average monocyte count in birds affected with helminths was 9.60±0.20 % and in uninfected birds was 5.92±0.11 %. Studies on biochemical profile revealed significantly (P< 0.05) lower serum total protein concentration due to GI parasitic infection as compared to healthy birds. The overall mean total serum protein recorded in GI parasitic infected birds was significant (P<0.05) lower as compared to healthy birds (2.64±0.7 and 3.71±0.04 gm %). The overall mean value of AST and ALT in GI parasites infected birds was 72.36±0.25 and 8.51±0.09 U/I, and in healthy birds 68.41±0.42 and 6.71±0.10 U/I, respectively. The overall mean serum alkaline phosphatase (AKP) activity recorded in infected birds was 814.54±4.39 and in healthy birds it was 764.09±1.91 KAU/100 ml. The overall mean serum acid phosphatase (ACP) activity recorded in infected birds was 35.22±0.28 KAU/100 ml and in healthy birds it was 23.28±0.30 KAU/100 ml. A non-significant increase in AST, ALT, AKP and ACP activities was noticed in infected birds as compared to healthy birds. The overall means A: G ratio recorded in infected birds was 0.61±0.01 and in healthy birds it was 0.75±0.04. Histopathologically, gross lesions in Raillietina spp. infection was characterized by nodule formation on duodenal mucosa. Necrotic foci, pin point haemorrhages, rough and pale mucosa of duodenimi. Microscopical lesions included villous atrophy, desquamation of epitheliimi, catarrhal enteritis, granuloma formation in duodenum, congestion, cellular infiltration, desquamation of submucosal glands and haemorrhagic exudate were observed. In case of Ascaridia galli infection, lesions were characterized by haemorrhagic enteritis, anaemia, severe diarrhoea, young parasites penetrate the duodenal or jejimal mucosa, inflammation and thickening of intestinal mucosa were found due to continuous penetration done by young larvae. Necrotic foci were seen over the intestinal mucosa whereas the embedded larvae cause haemorrhage and extensive destruction of the glandular epitheliimi. hi case of Heterakis gallinarum, the macroscopical lesions were thickening of caecal wall, hemorrhagic exudate and cheesy core in caecal lumen. Severity grades of microscopical lesions were: severe hyperplasia of tunica muscularis, massive lymphocyte, heterophil and macrophage infiltration with coagulative necrosis. In case of intestinal coccidiosis, the exterior of intestine showed reddish white pinpoint foci on its wall, especially in the initial part of the small intestine. The intestinal contents were liquid and mixed with variable quantity of mucous, while some show streaky haemorrhages. Catarrhal enteritis with blood tinged mucous exudates during moderately heavy infections of coccidia in birds and diffused or localized areas of coagulation, necrosis and sloughing of the mucosa in severe infections. In case of caecal coccidiosis, gross lesions were characterized by distention of caecal pouches with blood clots and reddish brown contents in haemorrhagic type of infection. Caecal walls were thickened, congested, extensive vacuolations in the glandular epithelial cells with increased goblet cells activity were observed. Histopathologically, intense hyperaemia of the caecal mucosa and patchy areas of haemorrhages were observed.
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    ThesisItemOpen Access
    STUDIES ON CLINICO-BIOCHEMICAL ASPECTS OF ANCYLOSTOMOSIS IN DOGS
    (AAU, Anand, 2015) BRAHMBHATT, NILIMABEN N.; Patel, P. V.
    The study was carried out to ascertain the monthwise, seasonwise, agewise, breedwise, sexwise and overall prevalence as well as haemato - biochemical and histopathological aspects of Ancylostomosis in dogs at Anand District of Gujarat. The study was undertaken for the period of twelve months from March-2014 to February- 2015. The faecal samples and intestinal contents were collected from the dogs brought to the hospital of Veterinary College (TVCC) and the surrounding areas of Anand district. Faecal samples were collected during anti-mortem examination and intestinal contents were collected during post-mortem examination of dogs. For recording / findings of prevalence, faecal samples and intestinal contents of dogs were collected for the detection and identification of eggs of Ancylostoma spp. as per standard method. The clinical signs were observed in dogs during Ancylostomosis were diarrhoea and anaemia accompanied by hydraemia, sometimes oedema, general weakness and emaciation. The faeces are often diarrhoeic and contain bloody mucus or they may be of a tarry nature. A total of 392 faecal samples were collected from Anand district out of which 90 faecal samples were found positive with the seasonal prevalence of 29.50% in summer,24.81% in monsoon and 15.03% in winter. The highest prevalence rate was observed in the month of May 36.66%) and lowest in the month of December 13.79%) from the faecal samples. The agewise prevalence of 36.02%) in young age, 16.15%) in middle age and 10.89% in old age. The sexwise prevalence of 29.41% in male and 14.61%) in female and the breedwise highest prevalence of Ancylostomosis were noticed 42.85%) in mongrel and lowest 14.10%) in doberman by examining faecal samples of Anand district. The overall prevalence rate was found to be 22.95% (90) for the faecal samples of Anand district. Ancylostomosis affects the haematological values of the host. The haematological parameters viz. haemoglobin (Hb), packed cell volume (PCV), total erythrocyte count (TEC), total leulcocytes count (TLC), different leukocyte count (DLC), mean corpuscular volume (MCV), mean corpuscular haemoglobin (MCH) and mean corpuscular haemoglobin concentration (MCHC) were smdied from Ancylostoma spp. infected and non-infected dogs.
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    ThesisItemOpen Access
    STUDIES ON PREVALENCE, HAEMATO- BIOCHEMICAL AND HISTOPATHOLOGICAL ASPECTS OF AMPHISTOMOSIS IN SLAUGHTERED BUFFALOES.
    (AAU, Anand, 2014) CHAUHAN, VANDIP D.; PATEL, P. V.
    The study was carried out to a certain the prevalence, haemato-biochemical and histopathological aspects of amphistoniosis in slaughtered buffaloes at Anand and Ahmedabad Districts of Gujarat for the period of twelve months from March-2013 to February-2014. The faecal samples and intestinal contents were collected in small and clean sterilized polythene bags from the buffaloes brought to the slaughter house of Anand and Ahrnedabad districts and brought to the department of Parasitology and processed for standard qualitative examination. The direct, sedimentation and floatation technique were used to detect the presence and identification of amphistome eggs in the samples. Blood samples from 50 amphisiomes infected as well as 50 non-infected buffaloes were taken during the anti-mortem examination for hematological analysis and to separate serum for analysis. Various serum, biochemical parameters like Total protein. Albumin, Globulin, A:G ratio. Alkaline Phosphatase (AKP),Acid Phosphatase (ACP), Aspartate Aminotransferase (AST), Alanine Aminotransferase (ALT) and Total Bilirubin along with various hematological parameters like TEC, TLC, DLC, PCV and Hb were analysed through automatic analyser. For Histopathological study, a total of 30 positive amphistomes infected liver, rumen and intestine were collected from slaughter houses of Anand and Ahmedabad districts. Tissue pieces of rumen and liver preserved in 10% neutral buffered formal saline solution and were processed by paraffin embedding method and stained with Ehrlich's Haematoxylin aad Eosin. Formalin preserved parasites were processed by paraffin embedding method and stained by H & E stain as per Luna (1968). The prepared sections were examined by microscopy and-microphotography in order to identify anterior and posterior suckers, pharynx, uterus etc. A total of 758 faecal and 721 liver/rumen samples were collected at Anand district out of which 214 faecal and 198 liver/rumen samples were found positive with the seasonal prevalence of 21% (summer), 29.62% (monsoon) and 32.84% (winter) for the faecal samples and 20.11% (summer), 28.57% (monsoon) and 34.66% (winter) for the liver/'rumen samples. A total of 798 faecal and 790 liver/rumen samples were collected at Ahmedabad district out of which 221 faecal and 228 liver/rumen samples were found positive with the seasonal prevalence of 19.73% (summer), 29,43%) (monsoon) and 32.29% (winter) for the faecal samples and 24.15% (summer), 28.94%) (monsoon) and 32.63% (winter) for the liver/rumen samples. The overall prevalence rate was found to be 28.23% (214) and 27.46%) (198) for the faecal and liver samples at Anand district and 27.69% (221) and 28.86% (228) for faecal and liver samples at Ahmedabad district.
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    ThesisItemOpen Access
    Diagnosis of Tropical Theileriosis in cattle and buffaloes using advanced molecular tools
    (AAU, Anand, 2013) KUNDAVE, V. R.; PATEL, P. V.
    The study on "Diagnosis of Tropical Theileriosis in cattle and buffaloes using advanced molecular tools" was carried out to effectively diagnose Theileria annulata by Poljmierase Chain Reaction and its quantification by real-time PCR assay in infected and carrier animals. Bovine tropical theileriosis caused by Theileria annulata is a tick-borne disease, associated with high morbidity and mortality rate in the livestock and pose a great threat to the farmers and dairy industry in India. The diagnosis by microscopic examination, has low sensitivity and it is difficult to detect the piroplasms in the carriers, while the PCR based assays are more sensitive. In this study a total of 116 samples, were collected from infected as well as apparently healthy cattle and buffaloes, 74 samples (63.79 per cent) were positive for Theileria annulata by PCR, which includes 15 samples that were positive by giemsa staining. The primers were designed to amplify the Tamsl gene encoding the 30- kDa major merozoite surface antigen of T. annulata. A product size of 430-bp afi:er amplification by Polymerase Chain Reaction (PCR). Highestprevalence was recorded in cattle above 5 years of age (82.35 percent) and the lowest prevalence was recorded in calves less than 1 year of age (14.28 per cent). A SYBR Green-based real-time PCR assay was carried out to quantify the load of parasites in positive samples. The parasitic load ranged from 1000 to 34,00,000 and 300 to 29,000 per microlitre of blood in cattle and buffalo samples, respectively, indicating the sensitivity of the diagnostic assay and also the degree of infection in the infected as well as carrier animals. The clinical signs suggestive of tropical theileriosis were more prominent in the acute phase of infection, which was also characterized by high levels of parasitaemia while their occurance in low level was found in the blood of carrier animals. The study undertaken suggests that the difficulties faced in detection and differentiation of Theileria piroplasms by conventional staining method could be overcome by the molecular methods like PCR. Real-time PCR assay could be used as a sensitive and accurate method to detect and quantify the parasitic load in the blood of cattle and buffaloes. PCR assays are advantageous since it has the ability to detect the disease in carrier animals and animals in chronic phase of theileriosis.
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    ThesisItemOpen Access
    A STUDY ON HELMINTH PARASITES OF BUFFALOES BROUGHT TO AHMEDABAD SLAUGHTER HOUSE
    (AAU, Anand, 2012) PATEL, HARISHKUMAR CHATURBHAI; Hasnani, J. J.
    Gujarat is one of the leading states in agriculture and showing high growth rate since last few years. Animal husbandry had played crucial and vital role in achieving such attractive growth rate. Present study was planned and executed in order to help the progressive farmer of state and findings may help to make their animal rearing profitable. On based of this study, the general prevalence rate of helminth parasites in buffaloes was found to 64.67% on screening of 150 samples, like faecal sample, affected tissues, abomasal content and other samples as per necropsy lesions were collected with proper care. On class wise analysis it was revealed that 64 % cases are of trematodes, followed by nematodes and cestodes with 26% and 10%, respectively. On species wise analysis, it was found that the prevalence of Fasciola gigantica was the highest (15.33%) and that of Moniezia benedeni was the least (2.66%) among eight observed species. On quantitative examination of faecal samples, it was revealed that the egg counts for all observed species were ranged between 100 to 1400; with maximum count for F.gigantca and lowest for Sirongyle group . On age wise analysis, it was revealed that the prevalence of helminth was maximum (46.39%) in young age group; followed by adult (27.83%). and old animals (25.77%). On season wise analysis, it was observed that the rainy season (51.54%) has highest prevalence followed by winter (34.02%) and summer (14.43%)); similar findings were also observed for faecal egg counts. On gross examination; rumen, bile duct, intestine and liver were found infested with various helminth parasites viz; Fasciola giganica, Paraamphistomum cervi, Gigantocotyle explanatum etc. And on histopathological examination various changes like infiltration of lymphocytes, the thickening of hepatic capsule, presence of mononuclear cells, proliferation of fibroblasts etc. were noticed.
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    ThesisItemOpen Access
    COMPARATIVE EFFICACY OF COCCIDIOSTATS ON EXPERIMENTALLY INDUCED EIMERIA TENELLA INFECTION ALONG WITH EFFECTS ON GROWTH HAEMATO-BIOCHEMISTRY AND PATHOLOGY IN BROILERS
    (AAU, Anand, 2014) HIRANI, NITINKUMAR DEVRAJBHAI; Hasnani, J. J.
    The efficacy of three commonly used feed coccidiostats named Diclazuril (T1) Salinomycin (T2), Diclazuril + Salinomycin (T3) in shuttle programme and Maduramicin (T4) on experimentally induced Eimeria tenella coccidial infection and their effects on growth, haematology, biochemical and histopathological changes were undertaken in three hundred Cobb400 strain of broiler at University Poultry Complex, Anand Agricultural University, Anand during year 2012. Birds were given feed containing Diclazuril (T1), Salinomycin (T2), and Maduramicin (T4) coccidiostats at dose rate of 1 ppm, 60 ppm and 5 ppm upto 42 days. Weekly body weight and feed consumption were recorded. Various parameters considered for comparative efficacy were studied. Experimental infection of 50,000 oocysts of E.tenella was given on 22nd day of age. Blood was collected before experimental infection at 3 weeks and after experimental infection at 4 weeks of age for haemato-biochemical study. The results of faecal score, oocyst per gram (OPG), lesion score, oocyst index value and mortality indicated better efficacy of coccidiostats as compared to non medicated birds in experimental infection with better efficacy of Maduramicin and Salinomycin as compare to Diclazuril and Diclazuril + Salinomycin shuttle treatment. Coccidiostats proved to have growth promoting action in broiler chickens during the experimental infection. Birds fed with Maduramicin medicated (5 ppm) performed well in terms of live weight gain and feed conversion ratio and it was followed by salinomycin (60 ppm) for weight gain and Diclazuril (Ippm) for feed efficiency in broiler birds. Result of sensitivity against E. tenella indicated good efficacy of Maduramicin (82%), whereas limited efficacy of Salinomycin (76%), Diclazuril (74%) and Diclazuril + Salinomycin Shuttle group (71%)) on the basis of Global index value (GINNC % ) Haematological studies revealed that haemoglobin concentration, packed cell' volume and total erythrocytes counts were significantly (P < 0.05) reduced, while total leukocytes counts were significantly increased on account of coccidial infection in all coccidiostat treatment and infected non treated groups. Different Leukocytes Count (DLC) value revealed significant increase in heterophills, lymphocytes and eosinophills and significant decrease in monocytes and basophills on account of coccidial infection. Results on haematological studies indicated comparatively less pathological damage by Salinomycin. Studies on biochemical profile revealed significantly (P < 0.05) lower serum glucose and serum total protein, while significant increase in serum total cholesterol. Serum Glutamic Oxalo-acetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT) and Alkaline Phosphatase (AKP) activities was observed due to coccidial infection as compared to pre infection levels in birds. Results of biochemical studies indicated comparative less pathological damage by coccidiostats treatment as compared to infected non treated group, but there was no consistent trend for drug choice. From histopathological study it was clear that the Maduramicin and Salinomycin treated group showed very less mechanical damage to tissue hence it could be used as a curative remedy against the caecal coccidiosis. The presence of clusters of large schizonts in the caecum was pathognonomic for E. tenella. The magnitude of infection type and dose of coccidiostat and stage of development of the disease could be established by histopathological observation.