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  • ThesisItemOpen Access
    CANINE PYODERMA : DIAGNOSIS AND THERAPEUTIC MANAGEMENT
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) MARAK, SABETINI S.; Changkija, Bendangla
    The present study entitled “Canine pyoderma: Diagnosis and therapeutic management” was undertaken w.e.f. 1st August 2018 to 31st May 2019 with the objective to study the prevalence, identification of causative organism, hemato-biochemical alteration and to assess therapeutic efficacy in canine pyoderma. The overall prevalence of pyoderma in dogs was 14.59% with higher occurrence in Labrador breed (40%) with males (63.75%) being predominantly affected and in age group below 1 year (33.75%). Clinical signs associated with canine pyoderma were pruritis, pustules, alopecia, papule, scale and crust, patches, erythema, moth eaten appearance, dry coat, epidermal collaret, hyperpigmentation, abscess, lichnefication, edema, erosion and fissure. The causative organisms isolated from canine pyoderma were Staphylococcus species (100%) of which highest was Staphylococcus intermedius (43.75%) followed by Staphylococcus aureus (13.75%), coagulase negative Staphylococcus species (12.5%), Staphylococcus intermedius and Staphylococcus aureus (5%), Staphylococcus intermedius with Pseudomonas species (6.25%) and Staphylococcus intermedius with Klebsiella species (11.25%), Staphylococcus aureus with Pseudomonas species (5%) and Coagulase negative Staphylococcus species and Pseudomonas species (2.5%). The antibiotic sensitivity test for Staphylococcus intermedius isolates revealed highest sensitivity to linezolid (100%); Staphylococcus aureus to cephalexin and linezolid (94.73%); Coagulase negative Staphylococcus species to cephalexin and linezolid (100%); however gram negative organisms like Pseudomonas species and Klebsiella species revealed highest sensitivity to enrofloxacin (100%) but complete resistant to cephalexin and linezolid. Hematobiochemistry revealed anaemia (Low Hb and TEC), leukocytosis, neutrophilia, reduction in serum albumin, A:G ratio and zinc when compared with apparently healthy dogs. Dogs treated with cefpodoxime, ceftriaxone and tazobactum and linezolide showed faster recovery in clinical symptoms weekly than that of cephalexin and enrofloxacin but complete remission of clinical signs in all the animals was observed only in cephalexin treated group.
  • ThesisItemOpen Access
    MANAGEMENT OF HYPOVITAMINOSIS-D FOR THE PREVENTION OF PERIPARTURIENT HYPOCALCAEMIA IN DAIRY COWS
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) PATEL, NISHA MANISH; Baishya, B. C.
    The present study entitled “Management of hypovitaminosis-D for the prevention of peri-parturient hypocalcaemia in dairy cows” was undertaken w.e.f. 1st September, 2018 to 31st March, 2019. The objectives of the study were to know the status of vitamin-D and calcium in crossbred dairy cows reared under intensive system, along with alterations of serum levels of related minerals and biochemical parameters associated with peri-partum hypocalcaemia and to assess the efficacy of parentrally administered synthetic analogue of vitamin-D for the prevention of peri-parturient hypocalcaemia. From the study, the prevalence of pre-partum hypocalcaemia in crossbred dairy cows was recorded as 33.33%, with a higher occurrence (34.48%) in Jersey crossbred cows compared to HF crossbred cows (32.55%) and a predominance in cows of 6-8 years age (40.90%). However, there were statistically no significant differences in prevalence between the two breeds and among the different age groups. The only observed clinical signs associated with the recorded hypocalcaemia were lowered appetite and a rough body coat. Biochemical studies revealed a significant increase (P<0.01) in the levels of serum total vitamin-D (cholecalciferol), blood urea nitrogen and creatinine, which reduced significantly (P<0.01) after treatment to the levels of the control group towards at the end of the study. A significant increase (P<0.01) was recorded in the levels of serum calcium and phosphorus after treatment however, no abnormal variation was recorded in the levels of serum magnesium throughout the study. Use of synthetic (α) analogue of vitamin-D (cholecalciferol) was found to be effective in increasing the serum calcium level and thereby preventing the occurrence of peri-parturient hypocalcaemia in crossbred dairy cows.
  • ThesisItemOpen Access
    PREVALENCE OF EYE DISEASES IN DOG WITH SPECIAL REFERENCE TO BACTERIAL INFECTION
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) DAS, DIBYAJYOTI; Phukan, A.
    Ocular disease is a common problem in dogs, occurs mostly due to bacterial infection, trauma, injury, viral infection, allergic condition, vitamin deficiency, old age and hereditary. In the study period 9138 numbers of dogs were screened and ocular disease was recorded in 71 numbers of dog. The prevalence of ocular diseases in dog was recorded 0.78%. On the basis of clinical categorization, the highest prevalence of ocular disease was recorded as conjunctivitis (49.29%) and lowest in corneal opacity (7.05%). In the present study, the highest affection of eye was recorded in both eye (45.07%) and highest clinical findings recorded in congested mucous membrane (84.50%. The season wise prevalence of ocular disease in dogs was highest in winter (45.07%) and lowest in pre-monsoon (8.45%) season. In present study sex wise prevalence of ocular diseases were more in male (64.78%) than female (35.22%).Age - wise prevalence was highest in the>3 years – 6 years (29.58%) age group and lowest in below 1 year (4.22%) age group and breed wise prevalence the highest was recorded in German Shepherd (19.72%) and lowest in Boxer (2.82%). The most common species of bacteria isolated were Staphylococcus (22.39%), Streptococcus (19.40%) and Pseudomonas (8.95%) species. More number of coagulase positive Staphylococcus species were recorded. Staphylococcus and Streptococcus species were mostly isolated from conjunctivitis condition and Pseudomonas species were highest isolated from keratitis condition. The sensitivity pattern of the isolates showed highest sensitivity to ciprofloxacin whereas less sensitive to ofloxacin. For therapeutic management of bacterial infection (conjunctivitis and keratitis) of eye, 36 dogs were randomly divided into 2 groups, Group I and Group II. In group I, ciprofloxacin was found effective on 14th day post-treatment in subgroup A and C dogs and in group II, gentamicin was found effective on 14th day post-treatment in subgroup D and F dogs.