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Subject: Clinical Veterinary Medicine, Ethics and Jurisprudence × Author: PATEL, NISHA MANISH × End date: 2019 × Start date: 2019 ×
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    ThesisItemOpen Access
    MANAGEMENT OF HYPOVITAMINOSIS-D FOR THE PREVENTION OF PERIPARTURIENT HYPOCALCAEMIA IN DAIRY COWS
    (College of Veterinary Science, Assam Agricultural University, Khanapara, Guwahati, 2019-07) PATEL, NISHA MANISH; Baishya, B. C.
    The present study entitled “Management of hypovitaminosis-D for the prevention of peri-parturient hypocalcaemia in dairy cows” was undertaken w.e.f. 1st September, 2018 to 31st March, 2019. The objectives of the study were to know the status of vitamin-D and calcium in crossbred dairy cows reared under intensive system, along with alterations of serum levels of related minerals and biochemical parameters associated with peri-partum hypocalcaemia and to assess the efficacy of parentrally administered synthetic analogue of vitamin-D for the prevention of peri-parturient hypocalcaemia. From the study, the prevalence of pre-partum hypocalcaemia in crossbred dairy cows was recorded as 33.33%, with a higher occurrence (34.48%) in Jersey crossbred cows compared to HF crossbred cows (32.55%) and a predominance in cows of 6-8 years age (40.90%). However, there were statistically no significant differences in prevalence between the two breeds and among the different age groups. The only observed clinical signs associated with the recorded hypocalcaemia were lowered appetite and a rough body coat. Biochemical studies revealed a significant increase (P<0.01) in the levels of serum total vitamin-D (cholecalciferol), blood urea nitrogen and creatinine, which reduced significantly (P<0.01) after treatment to the levels of the control group towards at the end of the study. A significant increase (P<0.01) was recorded in the levels of serum calcium and phosphorus after treatment however, no abnormal variation was recorded in the levels of serum magnesium throughout the study. Use of synthetic (α) analogue of vitamin-D (cholecalciferol) was found to be effective in increasing the serum calcium level and thereby preventing the occurrence of peri-parturient hypocalcaemia in crossbred dairy cows.