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20171
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Subject: Clinical Veterinary Medicine, Ethics and Jurisprudence × Author: Brahma, Juripriya × End date: 2019 × Thesis Type: M.V.Sc. ×
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    ThesisItemOpen Access
    THEILERIASIS IN CATTLE AND ITS THERAPEUTIC MANAGEMENT
    (College of Veterinary Science, Assam Agricultural University Khanapara, Guwahati-781022, 2017-07) Brahma, Juripriya; Baishya, B. C.
    The study was undertaken w.e.f. 1st March 2016 to 28th February 2017, to study about the theileriasis in cattle and its therapeutic management. A total of 275 out of 563 suspected animals were found positive only for Theileria orientalis infection and the prevalence was recorded 48.84 per cent. Season-wise prevalence of Theileria orientalis was recorded highest in monsoon (53.85%) in comparison to other seasons. The highest prevalence of 60.19 per cent was recorded in the age group of above 3 years. The Holstein Friesian crossbred recorded highest with prevalence of 54.04 per cent. The noted clinical signs were fever, respiratory distress, anorexia, reduced milk yield, nasal discharge, depression, pale mucous membrane, diarrhoea, icterus and changes of urine colour. Though PCR analysis was found more sensitive in detecting the Theileria orientalis infection, the microscopic examination was found as gold standard for diagnosis of clinical theileriasis. The level of haemato-biochemical parameters like haemoglobin, packed cell volume, monocytes, basophils, total erythrocyte count, creatinine and blood urea nitrogen were found significantly decreased (P<0.01), and the levels of total leucocyte count, neutrophils, eosinophils, aspartate aminotransferase, alanine aminotransferase, total bilirubin and direct bilirubin were found significantly increased (P<0.01). Among the different treatment regimens used, the buparvaquone was found most effective and followed by buparvaquone with immunomodulator, oxytetracycline with diminazine diaceturate, and a combination of oxytetracycline and diminazine diaceturate with immunomodulator. Considering the alteration in pre and post treatment parameters like parasitological examination, haemato-biochemical examination and therapeutic efficacy, either the combination of oxytetracycline and diaminazine diaceturate or oxytetracycline, diaminazine diaceturate with immunomodulator also can be used alternatively for the treatment of oriental theileriasis.