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Subject: Veterinary Medicine × Author: KAU × End date: 2000 × Type: Thesis × Thesis Type: M.V.Sc. ×
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Now showing 1 - 9 of 19
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    ThesisItemOpen Access
    Studies on mastitis in goats
    (Department of Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1978) Venugopal, K; KAU; Paily, E P
    In the present investigation, milk samples from 56 clinical and 379 apparently normal goats were examined. Staphaurous was isolated from 52 percent of clinical cases. The other organisms isolated were, starph. Epidermidis, str, agalactiae, C.pyogenes, K.pneumoniae, Esch. Coli, Ent.aerogenes and P.aeruginosa. The samples examined from apparently normal goats revealed an incidence of 47 percent subclinical mastitis. Mastaid Test conducted on milk samples from apparently normal goats revealed that this test was 96.5 percent efficient in detecting subclinical mastitis. From the somatic cell counts performed on milk samples, it was observed that normal milk (CMT Zero) had a mean cell count of 0.9 lakhs per ml. The cell counts of 5 to 10 lakhs (CMT + ) represented subclinical mastitis. When a comparative study was conducted study was conducted with mastrid test, whiteside test and tcepol mastitic test it was observed that mastaid reagent could only be relied upon in detecting subclinical mastitis. Chloramphenicol was found to be the drug of choice in goat mastitis, as evidenced by the in vitro sensitivity tests. Erythromycin, Ampicillin, Terramycin and Pencillin were moderately efficient. Results of the treatment with sensitive drugs on 40 selected clinical cases have been discussed.
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    ThesisItemOpen Access
    Effect of ascaridia galli infection on newcastle disease (Ranikhet Disease) vaccination
    (Department of Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1981) Vikraman, V; KAU; Paily, E P
    Under controlled conditions, the effect of Ascaridiasis on Newcastle disease vaccination was investigated. Haematological studies revealed reduction in erythrocytes, haemoglobin, serum protein, heterophils and basophils and an increase in leukocytes and eosinophils in A. galli infected birds. Post – vaccinal reactions, mostly of a paralytic nature, were observed in 25 – 30 per cent of the infected birds. The immune response of birds to Newcastle disease as revealed by the HI titres, is reduced by A. galli infection, the magnitude of reduction being related to the severity of worm burden. Although, all the birds resisted challenge, A. galli infected birds developed a mild form of disease. The need for routine deworming of birds before vaccination is stressed.
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    ThesisItemOpen Access
    Incidence of leukaemia and leukaemoid reactions in cattle in Kerala
    (Department of Therapeutics, College of Veterinary and Animal Sciences, Mannuthy, 1980) Vijayan, R; KAU; Krishnan, Nair M
    The present study was taken up to investigate the incidence of leukaemia and leukaemoid reactions in cattle in Kerala, utilizing 550 animals from selected private and Government farms and Veterinary institutions of the state. For the haematological diagnosis Benedixen’s key was followed. The haematological values of all the animals examined fell within the category of normal animals and it could be said that bovine leukaemia was not encountered in the bovine population screened in the present investigation. None of the samples showed any evidence of leukaemoid reactions. A few animals with enlarged lymphnodes showed lymphocyte per cent above 80 but their absolute lymphocyte values were within the normal range. The lymphocytes in the blood smears did not show any cytological abnormalities to indicate noeplastic property.
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    ThesisItemOpen Access
    Study on the incidence of brucellosis in buffaloes in Trichur
    (Department of Preventive Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1978) Baby, K; KAU; Paily, E P
    The result of an investigation, carried out on 1026 buffaloes in and around Trichur, to assess the incidence of brucellosis in buffaloes was recorded. Standard serum tube agglutination test was carried out on the blood samples collected from 590 animals in and around Trichur, 146 animals maintained in the three organised farms in the State and 290 animals slaughtered at the abattoir, Kuriachira, Trichur. Milk ring test was conducted on 115 individual samples of milk. The overall incidence of brucellosis in the buffalo population tested was 2.24 per cent. All the animals maintained in the organised farms gave a negative result to brucellosis. The possible methods of control and eradication of brucellosis in Kerala State were discussed.
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    ThesisItemOpen Access
    Studies on non-specific anorexa in cattle
    (Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1989) Baby, P G; KAU; Alikutty, K M
    Non – specific anorexia as a peculiar clinical syndrome in cattle was observed for the last one and a half decades in Kerala. Sample survey on the incidence of this syndrome was conducted through the selected veterinary hospitals in the field and of the Kerala Agricultural University. During the period of 1978 – 1982, anorexia syndrome in cattle constituted 10.95 per cent of the total and 32.30 per cent of their digestive disorders. The incidence of the syndrome was also noted high during the months of November to April every year. Ten apparently healthy cattle maintained under identical conditions of feeding and management at the University Livestock Farm, Mannuthy were selected at random and used as the control animals (Group I) for this study. Twenty selected clinical cases of non – specific anorexia presented at the University Hospital, Mannuthy were divided into groups of ten each (Group II and GroupIII) and utilized for these investigations. Course of the disease was followed and samples of rumen liquor and blood were collected and analysed on the first, third and fifth days of their admission in the clinic. Inappetance, mucopurulent nasal discharge, dryness of the muzzle, followed by peeling of its epithelium, constipation or diarrhea, weakness, emaciation and also marked reduction in milk yield in the lactating animals were the clinical manifestations noted in the affected animals. Their rectal temperature was normal, pulse weak and rapid, respiration normal but sometimes labored and visible mucous membranes were pale or became icteric in the later stages of the disease. Rate of rumen motility was reduced and feeble in strength with rumination remaining suspended. Animals of group II were given conventional therapy comprising oral administration of alksline stomachics. Animals of group III were given 25 per cent dextrose solution and vitamin B – complex with liver extract parenterally and stomachics orally on the first, third and fifth days of their admission in the clinic. Rumen liquor of animals of groups II and III was light yellow, olive green or greenish in colour, aromatic / offensive in odour and thick/thin in consistency on the first day of observation. Protozoal motility was poor (+) to vigorous (+++) and sedimentation activity time was prolonged significantly on the first day. The mean pH of the rumen Liquor of these animals was not significantly different from that of the healthy group. Increase in the ammonia nitrogen level and decrease in total volatile fatty acids concentration in the rumen liquor observed on the first day were significant. Blood glucose, total bilirubin, total protein, albumin and albumin/globulin ratio in the serum were changed significantly in animals with non – specific anorexia. Significant changes observed in the above parameters in group II animals were further enhanced on third and fifth days of observation. In group III animals, a decrease in the ammonia nitrogen level and increase in the total volatile fatty acids concentration in the rumen liquor observed on the third and fifth day of admission in the clinic was statistically significant. Blood glucose, albumin – globulin ratio in the serum were also increased significantly in group III animals on fifth day. Following modified line of therapy the animals of group III became normal within three to five days. Clinical improvement was indicated by increased appetite, revival of rumen motility and rumination and also increased milk yield in the lactating animals. Decrease in the ammonia nitrogen level and increase in the total volatile fatty acids concentration in the rumen liquor of group III animals were significant on fifth day of therapy. Increase in blood glucose, albumin, albumin ratio in the serum were also found to be statistically significant on the fifth day. The changes in the blood glucose, total bilirubin, total protein, albumin and albumin – globulin ratio in the serum indicated hepatic insufficiency possibly responsible for the anorexia developed in the diseased animals. The modified line of therapy was found to be superior to conventional therapy for the clinical management of non – specific anorexia in cattle.
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    ThesisItemOpen Access
    Evaluation of liver function in ruminal acidosis in goats
    (Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1988) Usha Narayana Pillai; KAU; Alikutty, K M
    The results and conclusions drawn from a study on ruminal acidosis carried out to determine the incidence of disease in the field and clinical signs, changes in rumen liquor, blood and urine during the course of induced disease are presented, Based on the results effect of ruminal acidosis on the functional status of the liver was assessed to strengthen the diagnostic – therapeutic approaches hither – to adopted. The available data on the incidence of disease collected from field Veterinary hospitals were utilized for analysis of digestive disorders in goats. Twenty apparently healthy cross – bred goats of either sex weighing 15.0 to 25.0 kg and of 1 – 3 years in age maintained under identical conditions of feeding and management at the University Livestock Farm (AICRP on Goats for Milk Production), Mannuthy were selected at random and utilized for the present study. They were divided into two groups of eight (Group – 1) and twelve (Group – 11) and fistulated by suitable surgical techniques. Animals of Group – 1 were used as healthy control for this study. Ruminal acidosis was induced in Group – 11 animals by intraruminal administration of crushed raw rice at @ 80 g/kg body weight. Course of the disease was followed and clinical observations were made daily. Rumen liquor, blood and urine samples were collected at 0, 24, 48, 72 and 96 hours of the experiment and analysed. Similarly samples were collected at 24 hourly intervals from animals of group – 1 and analysed to obtain the normal values. Digestive disorders constituted 57.69 per cent of all diseases in goats. The incidence of primary digestive disorders was 29.37 per cent with acid indigestion forming 18.07 per cent. Seasonal variations in the incidence of ruminal acidosis were significant , the highest incidence was recorded during summer followed by rainy and winter seasons. General depression, dullness, mild tympany, absence of reticulo – ruminal contractions, firm and doughy rumen on palpation, foul smelling diarrhoea, purulent nasal discharge, increased rates of pulse and respiration and signs of dehydration were the important clinical signs noticed in the study. Rumen liquor samples collected from Group – 11 animals at 24 hours after induction of the disease were creamy, faintly sour to distinctly sour odour and watery in consistency. These physical characters of rumen liquor persisted during the rest of the period of observations. Complete absence of protozoal motility and SAT could be observed by 24 hours after induction of the disease. Significant decrease in the pH and NH3 – N with associated increase in lactic acid level were observed in all the samples of rumen liquor while decrease in the TVFA level was significant from the 48th hour of experiment. Significant increase in the blood glucose, lactic acid, GOT, LDH, GDH and T ½ of BSP with associated decrease in A:G ratio, cholesterol and fractional clearance of BSP from plasma were observed in animals in which ruminal acidosis was induced. However, total protein, albumin, GPT and NH3 – N levels in blood did not show any significant variations. Changes in the A:G ratio, GOT, LDH, GDH levels in the blood and fractional clearance of dye from the plasma indicated hepatic insufficiency. Urine samples did not reveal presence of any pathological constituents but a linear relationship was maintained between the pH of urine and rumen liquor. Postmortem findings included peeling of rumen mucosae, congestion all along the gastro – intestinal tract, cardiac dilatation, petechial haemorrhage on myocardium, degeneration and necrosis of liver, distension of gallbladder with greenish – yellow tinged fluid and degeneration of kidney.
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    ThesisItemOpen Access
    Clinicotherapeutic studies on mycotic dermatitis in cattle
    (Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 2000) Arun Raphel, P; KAU; Jayakumar, K M  
    A study was designed in the Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy to understand the occurrence and etiology of virous dermatological problems in cattle. Clinico – pathological changes and the efficacy of virus lines treatment were also investigated. The occurrence for the period from January – 1994 to December – 1998 was found to be 4.49 per cent, 38.32 per cent of the cases being mycotic dermatitis, 31.95 per cent fly bite dermatitis/ ectoparasitic dermatitis and 29.73 per cent non – specific dematatological disorders. Detailed clinical examination of cattle with mycotic dermatitis revealed scaling, pruritis, alopecia, increased skin thickness and hypopigmentation of hairs. Presence of biting flies were also recorded. Skin scrapings collected and examined under microscope revealed presence of ectothrix arrangement of fungal spores. Organisms isolated by fungal culture were Trichophyton verrucosum T. mentagrophytes, Penicillium spp. And Aspergillus spp. Neutrophilia, eosinophilia, lower copper and zinc values in blood were observed in mycotic dermatitis. In fly bite/ectoparasitic dermatitis, along with lower copper values in blood, slightly lower albumin, albumin/globulin ratio and eosinophilia were detected. In animals with non – specific dermatological problems along with eosinophilia, lower values of haemoglobin, packed cell volume, total erythrocyte count, copper, zinc, total protein and albumin were recorded. Histopathological studies revealed chronic dermatitis, with marked lymphocytic infiltration, epidermal hyperplasia and shedding of keratinized scales in non – specific dermatological problems. In cases of mycotic dermatitis invasion of fungi beneath stratum corneum, hair follicle and hyperkeratosis, were noticed. Complete recovery was noticed in all animals treated with Cassia alata leaves paste and Bordeaux mixture – 1 per cent in 21 days. Seven out of eight animals responded to topical application of tincture iodine and glycerine (1:1).
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    ThesisItemOpen Access
    Metabolic profile of ketotic crossbred dairy cows
    (Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1999) Manoj Johnson; KAU; Balakrishnan, V S
    A study of the metabolic profile in ketotic cows in field conditions was undertaken. Twenty field cases of clinical ketosis in crossbred cows which attended the outpatient unit of university veterinary Hospital, Mannuthy selected at random, were utilized for the study. Similarly twelve healthy dairy cows of identical field conditions during the vulnerable period of ketosis., i.e., within two months of calving, selected at random 90nstituted the control group. Samples of b19od, urine and milk from both healthy and ketotic animals were collected and analysed for various parameters using standard methods. economic loss was also carried out. Analysis of Data collected from the diseased animals indicated a high incidence among Jersey crossbreds during summer. Cows aged three to six years and in their second or third lactation showed more incidence. Most of the ketotic cows were within the first five weeks of calving~ , Other than the usual signs ~eported by earlier workers, frequent falling down and biting of chain, rope and crossbars of the manger were also noticed. The clinical data were in physiological limits. Examination of haemoglobin (Hb) and packed cell volume (PCV) did not reveal any significant difference between ketotic and healthy cows. Biochemically blood glucose, phosphorus, magnesium and total protein, albumin and globulin showed significant decrease and blood urea nitrogen and ketone bodies in blood showed significant increase among diseased cows. However serum calcium, sodium and potassium did not vary significantly among the two groups. Urine and milk from the both the groups were examined and varying concentrations of ketone bodies were detected. Various managemental aspects for the prevention and control of ketosis were discussed.
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    ThesisItemOpen Access
    Clinico-therapeutic studies on mycotic dermatitis of dogs
    (Department of Clinical Medicine, College of Veterinary and Animal Sciences, Mannuthy, 1998) Vinu David, P; KAU; Baby, P G
    Incidence of mycotic dermatitis among the total canine cases presented at the University Veterinary ,Hospitals, Kokkalai and Mannuthy for a period from September 1996 to August 1998 was found to be 5.13 per cent. Among the total dermatological disorders 28.72 per cent had mycotic dermatitis. Age, breed and sex wise incidence were collected. This showed an increased incidence in adult dogs, mostly in German Shepherds and that too in females. Detailed clinical examination revealed scaliness, alopecia, pruritus and erythema in all cases. Lesions were r:' mainly localized, extremely variable in configuration and majority were distributed on head and limbs. Skin scrapings collected and examined under microscope showed the presence of ectothrix arrangement of fungal spores. Mean total and differential count of leukocytes were found to be within the normal range for all cases. A total of four dermatophytes and 17 non-dermatophytes were isolated by fungal culture. Dermatophytes isolated were three Microsporum gypseum and one Trichophyton mentagrophytes spp. Non-dermatophytes isolated were eight Penicillium, six Aspergillus and three Rhizopus spp. In vitro antifungal susceptibility tests on the fungal isolates obtained showed a high sensitivity to cinnamon oil at a dilution of 1 in 10, followed by ketoconazole at 20 ~g and Sphaeranthus indicus extract at 50 mg concentrations. Response to treatment trials conducted on dogs with mycotic dermatitis using ketoconazole o i.nt.ment; showed therapeutic response in five out of seven cases. No response was noticed in dogs even after the course of tr~atment with S. indicus extract. Complete recovery was noticed in all animals treated with cinnamon oil.