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Subject: Veterinary Medicine × Author: Joseph, C R × End date: 1979 × Start date: 1979 ×
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    ThesisItemOpen Access
    Clinical investigation on the seasonally occurring respiratory disease in goats
    (Department of Therapeutics, College of Veterinary and Animal Sciences, Mannuthy, 1979) Joseph, C R; KAU; Aleyas, N M
    Incidence of a seasonally occurring respiratory disease problem in goats is on the increase in recent years. Review of available literature revealed paucity of adequate information on the clinico – therapeutic aspects of this condition. The present study was takenuup to throw more light on them. A total of 65 clinical cases of respiratory disorders admitted to the University Veterinary Hospitals, Mannuthy and Trichur and Veterinary Dispensary, Ollur during the period November 1978 to February, 1979 were studied, keeping 10 apparently healthy goats of All India Co – ordinated Research Project on Goats for Milk Production as control. The investigation included collection of data on the incidence, clinical examination, culture and sensitivity tests of nasal swab, haematological examination and therapeutic trials with suitable chemotherapeutic agents in clinical cases. The data collected from the records maintained in the Veterinary Hospitals, Mannuthy and Trichur showed a high incidence of this condition during the period November to February. The condition usually started as an upper respiratory tract affection and gradually spread to the lower respiratory organs. The important clinical signs noticed were anorexia, emaciation, easily induced frequent dry cough, mucopurlent nasal discharge, rise or normal temperature, increased pulse and respiratory rates, inspiratory dyspnoea, abnormal sounds on auscultation and fall in milk yield in lactating animals. In vitro antibiotic sensitivity tests and efficacy of treatments in clinical cases showed that chloramphenicol is the drug of choice, followed by nitrofurantoin. If the disease can be treated sufficiently early with suitable chemotherapeutic agents nearly 100 per cent cure is possible. Bacterial isolates from apparently healthy animals were Staphylococcus, Streptococcus, Corynebacterium, Pasteurella, Escherichia and citrobacter spp. While staphyclococcus, streptococcus, corynebacterium, pasteurella, Escherichia and klebsiella spp. Were isolated from diseased animals. Leukocytosis, neutrophilia, lymphopenia and normal eosinophil count with a reduction in total erythrocyte count, haemoglobin and packed cell volume were observed in diseased animals. Anaemic changes were noticed even after getting clinical cure. Fall in total leukocyte count and neutrophil percentage towards normal and a slight increase in lymphocyte percentage was noticed on the date of discharge. Significant leukopenia was evident in chloramphenicol, nitrofurantoin, streptomycin, erythromycin and ‘Proxymer’ treated groups while in chlortetracycline and kanamycin groups no change was noticed. Significant neutropenia was noticed in chloramphenicol, chlortetracycline, nitrofurantoin, kanamycin and erythromycin groups whereas the difference was not significant in streptomycin group. Significant lymphocytosis was observed in all the groups treated except erythromycin group.