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1981 - 198911990 - 19982
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Subject: Others × End date: 2000 × Type: Thesis × Thesis Type: M.V.Sc. ×
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    ThesisItemOpen Access
    Effect of depuration on the meat quality of the marine clam Sunetta scripta (Linne)
    (Department of Processing Technology, College of Fisheries,Panangad, 1998) Nishi Dharan, S; Damodaran Nambudiri, D
    Sunetta Scripta harvested from Munabam area were subjected to depuration studies to find out whether purging had any effect on the meat quality of the clam. Result of biochemical analysis shows that the clam is a good source of various nutrients. Meat yield of clam was found to be 9.5%. Pathogenic bacteria was absent except E. coli ,. which is within the permissible limits. Depuration of clam did not significantly change the protein and glycogen content. But sand content was reduced to insignificant level within 24 hr depuration. When clams were exposed to a concentration of 109 ceUS/ml of Vibrio parahaemolyticus, there was progressive accumulation of the micro-organism and it accumulated on an average of 2.6xl05 cells/g within 6 hrs exposure. Though accumulated organism was not completely eliminated from the clams during purification in a laboratory depuration unit using U. V for sterilising the water, the number had reduced to more than 1000 fold during 48 hrs depuration. There was remarkable change in the sensory attributes and grittiness character of the clam after depuration
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    ThesisItemOpen Access
    Anti-ulcer activity of Ocimum sanctum (Thuiasi ) Musa (AAb Group,Nendran) and Withania somnifera(Amukkiram) in rats
    (Department of Pharmacology and Toxicology, College of Veterinary and Animal Sciences,mannuthy, 1998) Sanjay, D; KAU; Venugopalan, K
    The study was~conducted in adult albino rats of either sex to assess the comparative anti-ulcer effect of powder and alcoholic extract of Ocimum sanctum (leaves), Musa (AAB group, "Nendran", mature, unripe fruit) and Withania somnifera (root) with Famotidine, at different dose levels given orally for 10 days and, 20 days after induction of gastric ulcers with aspririn at the dose rate of 200 mg/kg body weight for 7 days orally. The doses of different plant preparation were fixed arbitarily (Table 1) . Table 1. Doses of oc imum sanct um leaves, Musa (AAB group •. Nendran" ) mature and unripe fruit, withania somnifera root and Famotidine (in mg/kg orally) were fixed as below Plants Alcoholic extracts 10 dayo treatment 20 days treatment Powder 10 days treatment . 20 days treatment Ocimum sanctum G( 1) G(2) G(3) G(4 ) G(5) G(6) G(7) G(8) 250 500 250 500 500 1000 500 1000 Nusa (MS group G(9) 0(10) G( 11) (3(12) G( 13) G( 14) G(15) G( 16) Nendran) 500 1000 500 1000 1000 2000 1000 2000 Withania G(l7 ) G(18) G( 19) G(20) G(21) G(22) G(23) G(24 ) somnifera 250 500 250 500 500 1000 500 1000 Famotidine 10 days treatment F(10) 20 days treatment F(20) 40 mg/kg p.o 40 mg/kg p.o Control group A (CG(A) I - Aspirin treated controls (200 mg/kg b.wt) Control group B (CG(B) I - Natural healing for 10 days Control group C (CG(C) I - Natural healing for 20 days Control group A [CG(A)] was given aspirin at the dose rate of 200 mg/kg body weight for 7 days and on the 8th day, the rats were sacrificed and number of ulcers and severity (ulcer score) were determined with the help of magnifying lens. 11 The ulcer index and healing index were calculated based on the formulae: Ulcer index = Number of ulcers + Ulcer + score % incidence Number of animal Ulcer index (control) CG(A) Healing index Ulcer index (control) CG(A) Ulcer index (drug) x 100 The control group B [CG(B)] and control group C [CG(C)] were administered aspirin orally for 7 days and they were maintained by normal feeding and watering without any treatment for 10 days and 20 days respectively to assess natural healing. Famotidine was taken as standard drug and given orally at the dose rate of 40 mg/kg body weight for 10 days and 20 days respectively. The anti-ulcer activity of plants under study was compared with Famotidine . . Haematological parameters such a erythrocyte count, total leukocyte count, differential count and haemoglobin count were decermined to assess any changes in the haemogram. Histopathological study was also conducted to evaluate the severity of ulceration and healing process. The result of the present study with O. sanctum leaf powder and alcoholic extract showed that none of the experimental groups produced statistically significant healing effects comparable to Famotidine groups. Observation with Musa (AAB group, "Nendran") unripe fruit powder and alcoholic extract have indicated that all experimental group under study with the plant have better healing effect than control group for 10 days. The alcoholic extract of Musa (AAB group, "Nendran") at the dose rate of 1000 mg/kg body weight for 10 days, 500 mg/kg body weight for 20 days and 1000 mg/kg body weight for 20 days produced healing comparable to Famotidine at the dose rate of 40 mg/kg body weight for 10 days and 20 days respectively. The result of healing obtained with W. somnifera root indicate that alcoholic extracts at the dose rate of 250 mg/kg body weight for 20 days and 500 mg/kg body weight for 20 days and powder at the dose rate of 1000 mg/kg body weight for 20 days are comparable with Famotidine groups administered for 10 days and 20 days respectively. All other experimental group under study with this plant produced healing comparable to Famotidine administered for 10 days. Haematological study revealed no significant change and all values fall within the normal range of blood value for the species under study. Histopathological study revealed various ulcer lesions and healing process.
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    ThesisItemOpen Access
    Lipid Transfer in Chicken Ovary
    (Department of Physiology and Biochemistry, College of Veterinary and Animal Sciences,Mannuthy, 1981) Mathew Thomas, KAU; Ramakrishnapillai, M G
    The formation of an egg in the avian reproductive tract is a complex phenomenon. The exact mechanisms involved in the transfer of lipids synthesized in the liver and transported by blood to the ovary are not quite well understood. Hence this investigation was undertaken to study the various aspects of lipid transfer in relation to egg yolk formation. Ten numbers each of clinically healthy White Leghorn female birds of five different age groups (30 – 54- days, 70 – 74 – days, 100 – 104 – days, 129 – 133 – days and 223 – 227 – days – old) were selected at random, for the study and reared under standard farm conditions. Another group of 40 White Leghorn pullets (100 – 104 – days – old) were also selected at random and divided into four different groups of ten each. The first group of birds received stilbestrol dipropionate (SD), second group SD and progesterone (PG), the third group SD, PG, and testosterone dipropionate (TD) and the fourth group received olive oil alone for ten days consecutively. Blood serum, ovary and liver were collected from all the birds slaughtered by decapitation. Total lipid content in liver and ovary were determined by the method of Meynard and Joslyn (1970) and that in the serum, after extraction with ether and methyl alcohol. Phospholipid was estimated by adopting the method of King and Wootten (1959) and the total cholesterol by the method of Zak (1957). The growing birds recorded a progressive increase in phospholipids in the ovary, liver and blood serum. But the pullets treated with exogenous sex hormones did not show any significant increase in the level of phospholipids in the ovary while that in the liver and blood serum were high. The cholesterol level in the ovary, liver and bloods serum were high. The cholesterol level in the ovary, liver and blood serum were high in the different growing birds. But, here also, the cholesterol content in the ovary did not reveal any significant increase in level in pullets treated with different combinations of hormones, but that in the serum and liver were elevated. However, in the case of total lipids, the ovary, liver and blood serum in the case of all categories of birds showed a significantly higher content as age advanced and on the administration of hormones. The synthesis of lipids by the liver is increased in response to increasing levels of hormones as a result of growth and development of the birds. The lipids, synthesized in the liver, are distributed by the circulating blood to all the tissues, including the ovaries. The increase in concentration of lipids in the ovary as the birds grew older is due to the increased lipogenesis in the liver and their augmented transport by the blood. However, the pullets under the influence of exogenous sex hormones exhibited a different response. In the case of phospholipids and cholesterol the ovarian levels were low while in the liver and serum the values were high. The low levels of these components in the ovary may be due to the lesser ovarian activity induced by the operation of the negative feed – back mechanism between the pituitary and the sex steroids administered. But this does not hold good in the case of total lipids in the ovary of pullets receiving sex hormones. Here the level was high as in the case of liver and serum indicating a total absence of the operation of the negative feed – back mechanism. This calls forth further studies to enlighten the phenomenon.