Browsing by Author "Vairamuthu, S"
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ArticleItem Open Access Biomarkers in canine renal disorders(2020) Subapriya, S; Vairamuthu, S; Chandrasekar, M, et al.,; TANUVASRenal problems in canines are of worrying concern to both pet owners and practitioners throughout the globe as death becomes inevitable if appropriate diagnostic and therapeutic intervention is not carried out at the earliest. Creatinine has been used as a gold standard for screening renal disorders for years in canines. Much research has been carried out to develop and standardise novel renal biomarkers which can effectively diagnose renal issues well in advance than the existing renal biomarkers. In this review, we will discuss the various attributes of existing, timetested renal biomarkers and the prospects of various newly developed and emerging renal biomarkers.ArticleItem Open Access Characterization of Campylobacter jejuni An Important Zoonotic Food Borne Pathogen from Mastitis Milk and Raw Milk Samples(2023-09) Sumedha Bobade; Vijayarani, K; Tirumurugaan, KG; Thangavelu, A; Vairamuthu, S; TANUVASABSTRACT Background: Campylobacter has emerged as an important zoonotic food borne pathogen of human and animals worldwide. Campylobacter is one of the most common bacterial enteropathogens of food borne origin in industrialized countries with C. jejuni being the most common species followed by C. coli. There are very few cases reported from mastitis therefore this study was aimed to determine the incidence of Campylobacter jejuni from from mastitis milk and raw milk samples. Methods: Total of 72 milk samples comprising mastitis milk (20) and raw milk (52) were collected. The samples were subjected to cultural examination, biochemical as well as molecular identification. The isolates were further subjected to phenotypic characterization by biochemical test and genotypic characterization by polymerase chain reaction. The isolates were subjected to PCR targeting hip O and MAP A genes. Result: The 52 samples showed growth on modified Blood Free Charcoal Cefoperazone Deoxycholate agar media and 18 (34.61%) samples showed typical morphological characteristics. The result revealed that 10 (19.23%) isolates were positive by phenotypic characteristic and 7(70%) by Polymerase chain reaction for C. jejuni. The outcome result showed that importance of Campylobacter jejuni in cattle, especially raw milk and milk from mastitis cows, as a potential source for transmission of Campylobacteriosis in human and dairy farm environment. This can cause acute bacterial gastroenteritis in humans and associated with foodborn infection, food safety and a serious public health threat.ThesisItem Open Access Clinical and Laboratory Parameters as Prognostic Indicators in Equine Colic(TANUVAS, 2012) Enbavelan, P.A.; TANUVAS; Suresh, R.V.; Nambi, A.P.; Vairamuthu, SThesisItem Open Access Clinical Characterisation, Assessment of Clinical Significance and Therapeutic Outcome of Supraventricular Tachyarrhythmias in Dogs(TANUVAS, 2012) Sivaprakasam, A; TANUVAS; Selvaraj, P; Nambi, A.P.; Vairamuthu, SArticleItem Open Access Clinical pregnancy toxaemia diagnostic indicators and therapeutic evaluation in goats(2021) Vijayanand, V; Balagangatharathilagar, M; Tensingh Gnanaraj, P; Vairamuthu, S; TANUVASOut of 516 adult non descriptive does brought to Veterinary University Peripheral Hospital, Madhavaram Milk Colony, Chennai – 51, during the period October 2016 to September 2018, 264 (51.16%) were treated for various medical conditions. Among the does treated, 72 does were in their last six weeks of gestation carrying twins/triplets and presented with the history of off feed. They were subjected to determination of blood beta hydroxybutyric acid (BHBA) concentration by means of a portable blood ketone and glucose monitoring system and qualitative urinalysis using urine dip stick. Does with beta hydroxybutyric acid level > 1.6 mmol/L were classified as clinical pregnancy toxaemic group (n = 12). The control animals were selected from adult Tellicherry does in the age group of 2 to 4 years maintained at a private goat farm (ECR Goat Farm), Injambakkam, Chennai. The clinical pregnancy toxaemic group (n = 12) were resorted to treatment with intravenous glucose therapy (5% Dextrose), parenteral therapy of Vitamin B1, B6 & B12 and oral administration of glycerine @ 25 ml twice daily. Of the twelve animals treated only four showed signs of improvement to therapy with a cure rate of 33%, while mortality was present in four does (33%) and the remaining four (33%) did not show any sign of recovery to therapy and hence the owners resorted to disposal of their animal. Reliable diagnostic indicators for detection of pregnancy toxaemia under field conditions include presence of ketone body in urine and blood BHBA (≥ 0.8 mmol/L).ArticleItem Open Access Clinical pregnancy toxaemia diagnostic indicators and therapeutic evaluation in goats(2021) Vijayanand, V; Balagangatharathilagar, M; Tensingh Gnanaraj, P; Vairamuthu, S; TANUVASOut of 516 adult non descriptive does brought to Veterinary University Peripheral Hospital, Madhavaram Milk Colony, Chennai – 51, during the period October 2016 to September 2018, 264 (51.16%) were treated for various medical conditions. Among the does treated, 72 does were in their last six weeks of gestation carrying twins/triplets and presented with the history of off feed. They were subjected to determination of blood beta hydroxybutyric acid (BHBA) concentration by means of a portable blood ketone and glucose monitoring system and qualitative urinalysis using urine dip stick. Does with beta hydroxybutyric acid level > 1.6 mmol/L were classified as clinical pregnancy toxaemic group (n = 12). The control animals were selected from adult Tellicherry does in the age group of 2 to 4 years maintained at a private goat farm (ECR Goat Farm), Injambakkam, Chennai. The clinical pregnancy toxaemic group (n = 12) were resorted to treatment with intravenous glucose therapy (5% Dextrose), parenteral therapy of Vitamin B1, B6 & B12 and oral administration of glycerine @ 25 ml twice daily. Of the twelve animals treated only four showed signs of improvement to therapy with a cure rate of 33%, while mortality was present in four does (33%) and the remaining four (33%) did not show any sign of recovery to therapy and hence the owners resorted to disposal of their animal. Reliable diagnostic indicators for detection of pregnancy toxaemia under field conditions include presence of ketone body in urine and blood BHBA (≥ 0.8 mmol/L).ArticleItem Open Access Clinical, Haemato-Biochemical and Molecular Findings of Babesiosis in Dogs(Excellent Publishers, 2019-01) Brahma, Juripriya; Chandrasekaran, D; Jayathangaraj, MG; Vairamuthu, S; Soundararajan, C; TANUVASCanine babesiosis is a hemoprotozoan parasite affecting dogs. The goal of this study was to provide an overview of molecular examination of babesiosis and heamato-biochemical changes in canine babesiosis infected dogs. In this study, 8 cases infected with Babesia were confirmed by means of hematological, biochemical and multiplex PCR. The most common clinical signs were anorexia, pale or icteric mucous membranes, high rise of temperature and dark urine colour. The haematological and biochemical parameters showed decrease level of RBC, Hb, PCV, Platelets level and increase level of WBC, ALT, ALP, Total bilirubin, BUN and creatinine value.ThesisItem Restricted CLINICO PATHOLOGICAL CHANGES OF ACUTE PANCREATITIS IN DOGS(2018) Mahadimane, Abhilaasha C; Chandrasekaran, D; Kavitha, S; Vairamuthu, S; TANUVASThe aim of the present study was to document the clinico pathological changes of acute pancreatitis in dogs and to compare various diagnostic modalities in the early diagnosis of acute pancreatitis in dogs. Suspected dogs with gastrointestinal disorders presented with clinical signs such as acute onset of vomiting, diarrhea and abdominal pain were screened for acute pancreatitis by hematology, serum biochemistry, coagulation profile, pancreatic enzymes and radiography. Forty suspected cases were referred for detailed ultrasonographic evaluation. Fourteen cases with typical ultrasonographic changes were subjected for SNAP cPL estimation. The present study was divided into two groups - Group I consisting of normal healthy dogs (Control) and Group II consisting of dogs with acute pancreatitis.ThesisItem Open Access Clinico-Pathological Evaluation of Pancreatitis in Dogs(TANUVAS, 2009) Ravi, R; TANUVAS; Nambi, A.P.; Srinivasan, S.R.; Vairamuthu, SThesisItem Open Access Clinicopathological Evaluation of Dogs with Hypertension(TANUVAS, 2010) Priyanka; TANUVAS; Thirunavukkarasu, P.S.; Nambi, A.P.; Vairamuthu, SThesisItem Restricted CLINICOPATHOLOGICAL EVALUATION OF INFLAMMATORY BOWEL DISEASE AND ITS MANAGEMENT IN DOGS(2018) Sandhya Bhavani, M; Kavitha, S; Gowri, B; Vairamuthu, S; Vijayarani, K; TANUVASThe study entitled “Clinicopathological evaluation of inflammatory bowel disease and its management in dogs” was carried out to study the clinicopathological changes of inflammatory bowel disease (IBD)in dogs, to assess the usefulness of endoscopy in the diagnosis of IBD and evaluating the therapeutic protocols in the management of IBD. Present study consisted of ten apparently healthy dogs and thirty three clinical cases. The parameters included in this study were clinical examination, haematology, serum biochemistry, faecal examination, radiography, ultrasonography, endoscopy, histopathology, PCR, flowcytometry and special diagnostic tests (serum CRP, cobalamin and folate).ArticleItem Open Access Clinicopathological profile of canine thrombocytopenia(2020) Subapriya, S; Vairamuthu, S; Bharanidharan, GR, et al.,; TANUVASPlatelets are the cellular elements in blood along with the erythrocytes and leukocytes. Both increase as well as the decrease in the number and functioning of circulating platelets is detrimental to life of the individual. Increase in the number and functioning of platelets lead to thrombosis in vital arteries and obstruct the blood flow. Decrease in the number and functioning of platelets lead to bleeding and death. Compared to human beings, canines are more often presented with more cases of platelet reduction or thrombocytopenia than thrombotic episodes. Hence this article is aimed at discussing the current concepts and understanding of the causes, mechanism, diagnosis and management of thrombocytopenia in dogs.ThesisItem Restricted CLINICOPATHOLOGICAL, ULTRASONOGRAPHIC EVALUATION AND THERAPEUTIC MANAGEMENT OF SUBACUTE RUMINAL ACIDOSIS (SARA) IN DAIRY CATTLE(2018) Mohammed Ismail, AL; Kavitha, S; Nagarajan, B; Vairamuthu, S; TANUVASSubacute ruminal acidosis (SARA) is defined as periods of moderately depressed ruminal pH, is one of the most common chronic digestive disorders, especially in well-managed dairy herds. The study was conducted at Large Animal Medicine-Out patient Unit of Madras Veterinary College Teaching Hospital to document clinical, haemato-biochemical, rumen fluid, milk and ultrasonographic changes and to assess the efficacy of treatment protocols in the management of SARA in dairy cattle. In the study, dairy cows with the history of reduced dry matter intake, drop in milk yield and diarrhoea were subjected to detailed physical examination, haemato-biochemical, rumen fluid analysis, serum haptoglobin estimation and ultrasonographic evaluation. Twenty two cows were found to have SARA based on rumen liquor pH ranging from 5.4-6.0. Twenty cows were selected and randomly subjected for treatment trial with oral Sodium bicarbonate at the dose rate of 250gms/ cow/ day and Saccharomyces cerevisiae at the dose rate of 25×109 CFU/ cow/ day for seven consecutive days.ThesisItem Open Access CLINICOPATHOLOGY AND MEDICAL MANAGEMENT OF HEMATURIA IN DOGS(TANUVAS, 2016) Priti Siddharth, Taksande; Gowri, B; TANUVAS; Vairamuthu, S; Thirunavukkarasu, PThe study on ‘Clinicopathology and medical management of hematuria in dogs’ was carried out to record the etiology, incidence and clinicopathological changes associated with hematuria in dogs and to carry out suitable medical management in various etiopathologieal conditions of hematuria in dogs.ThesisItem Open Access A Comparative Serological Analysis of Canine Leptospirosis in Pet and Homeless Stray Dogs(TANUVAS, 2011) Alwin, D; TANUVAS; Balachandran, C; Vairamuthu, S; Vijayarani, KThesisItem Open Access A COMPARATIVE STUDY OF CONENTIONAL SUTURE AND STAPLER ANASTOMOSIS FOR GASTRO-INTESTINAL SURGERY IN DOGS(TANUVAS, 2016) Ramya, R; Jayaprakash, R; TANUVAS; Ravi Sundar George; Vairamuthu, SThe study was carried out on 12 clinical cases of dogs that were brought to Madras Veterinary College Teaching Hospital, with a history of gastro-intestinal affections requiring surgical intervention. The cases were selected based upon inclusive and exclusive criteria respectively. Twelve dogs selected for the study were randomly divided into two groups of 6 each. Conventional suture method in group l animals and anastomotic stapler in group II animals with gastro-intestinal obstructions were performed.ArticleItem Open Access Comparative study of DFAT, cytology and histopathology in diagnosis of rabies(2021) Tamizharasan, S; Pazhanivel, N; Vairamuthu, S; TANUVASRabies was a fatal disease which was diagnosed by various diagnostic methods. In this study, samples were collected from brain of dogs suspected for rabies. Brain impression smear were subjected to direct fluorescent antibody technique. Cytological study was done for identification of Negribodies. Formalin fixed samples were processed and studied for histopathological lesions. Out of 10 samples collected, 7 samples showed positive for rabies. On comparison of above diagnostic techniques, dFAT and Cytology were 100% specificity with each other whereas histopathology had only 43.5%.ArticleItem Open Access Comparison of conception rate following CIDR ± post insemination treatment with CIDR in repeat breeder cows(2020) Reshma, A; Veerapandian, C; Sathiamoorthy, T; Arunmozhi, N; Vairamuthu, S; TANUVASThe high incidence of Repeat breeding is one of the most common problems faced by the farmers and veterinarians in India and it causes huge economic loss to the farmers. A total of 90 repeat breeder cows that were either brought to the Teaching Veterinary Clinical Complex, Veterinary College and Research Institute, Tirunelveli, or to the infertility camps at nearby villages of Tirunelveli formed the experimental animals for the present study. The repeat breeder cows were randomly and equally assigned to one of the three groups. viz. control (Group I; n=30) CIDR (Group II; n=30) and CIDR + post AI CIDR (Group III; n=30). The pregnancy status was checked 60 to 90 days post insemination by rectal palpation. The conception rate following controlled breeding with CIDR (group II) was (P<0.05) higher at 43.33 percent than untreated cows (Group I), with CIDR and post insemination treatment with CIDR (group III) was the highest at 63.33 percent than group I & II. Hence, Controlled breeding using CIDR and PGF2α in combination with post insemination CIDR therapy or alone could be used to improve the conception rate in repeat breeder cows under field conditions.